Postoperative changes after surgical mesh hernia repair: a pitfall in interpretation of 18F-FDG PET-CT

Abstract

With increasing use of synthetic mesh, awareness of variations in FDG PET-CT appearance is important to avoid false interpretation in cancer patients.

FDG Localization in Acellular Dermal Matrix, a Potential Cause of Nonpernicious Uptake Following Breast Reconstruction Surgery

“…Maximal intensity projection ( A ), transaxial PET ( B ), and transaxial CT ( C ) images demonstrate symmetric, moderately intense bands of FDG uptake outlining the lateral margin of the reconstructed breasts (arrows), corresponding to location of the ADM material, and reflecting cellular incorporation, neovascularization, and ongoing wound repair. Although ADM-related FDG uptake has not previously been described in the context of breast reconstruction, ADM-related uptake has been reported regarding middle-ear reconstruction 2 and hernia repair, exhibiting focal, linear, or nonuniform FDG activity 3 . Specific brands of ADM have a variable time course of incorporation; the ADM used in the current report has rapid incorporation, peaking at 14 days, 4 with well-formed granulomata and cellular incorporation seen at 42 days 5 …”

“…Although ADM-related FDG uptake has not previously been described in the context of breast reconstruction, ADM-related uptake has been reported regarding middle-ear reconstruction 2 and hernia repair, exhibiting focal, linear, or nonuniform FDG activity. 3 Specific brands of ADM have a variable time course of incorporation; the ADM used in the current report has rapid incorporation, peaking at 14 days, 4 with well-formed granulomata and cellular incorporation seen at 42 days. 5 FIGURE 2.…”