Postnatal renal tubule development: roles of tubular flow and flux
Yi-Jing G. Cheng,
Chien-Chou Chen,
Chih-Jen Cheng
Abstract:Purpose of review
Postnatal renal tubule development is critical to adult kidney function. Several postnatal changes regulate the differentiation and proliferation of renal tubular cells. Here, we review the literature and our efforts on thick ascending limb (TAL) development in Bartter syndrome (BS).
Recent findings
Glomerular filtrate quickly increases after birth, imposing fluid shear stress and circumferential stretch on immature renal tubules. Rece… Show more
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