Postnatal growth of preterm born children ≤750g at birth

Claas, M.J.; Vries, Linda S. de; Koopman, Corine; Venema, M.M.A. Uniken; Eijsermans, Maria J.C.; Bruinse, Hein W.; Stuart, A. A. Verrijn

doi:10.1016/j.earlhumdev.2011.04.009

Cited by 52 publications

(35 citation statements)

References 45 publications

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“…Previous data support the fact that HC catch-up growth has a significant beneficial effect on neuromotor scores and neurocognitive outcome [9,10]. By contrast, suboptimal HC postnatal growth is associated with impaired cognitive and psychomotor development [11].…”

Section: Introductionmentioning

confidence: 48%

Fetal and Postnatal Head Circumference Growth: Synergetic Factors for Neurodevelopmental Outcome at 2 Years of Age for Preterm Infants

Sicard¹,

Nusinovici

Hanf

et al. 2017

Neonatology

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Preterm infants present higher risk of non-optimal neurodevelopmental outcome. Fetal and postnatal growth, in particular head circumference (HC), is associated with neurodevelopmental outcome. Objectives: We aimed to calculate the relationship between HC at birth, HC delta Z-score (between birth and hospital discharge), and non-optimal neurodevelopmental outcome at 2 years of corrected age in preterm infants. Methods: Surviving infants born ≤34 weeks of gestation were included in the analysis. The relationship between the risk of being non-optimal at 2 years and both HC at birth and HC growth was assessed. The 2 Z-scores were considered first independently and then simultaneously to investigate their effect on the risk of non-optimality using a generalized additive model. Results: A total of 4,046 infants with both HC measures at birth and hospital discharge were included. Infants with small HC at birth (Z-score <-2 SD), or presenting suboptimal HC growth (dZ-score <-2 SD), are at higher risk of non-optimal neurodevelopmental outcome at 2 years (respectively OR 1.7 [95% CI 1.4-2] and OR 1.4 [95% CI 1.2-1.8]). Interestingly, patients cumulating small HC Z-score at birth (-2 SD) and presenting catch-down growth (HC dZ-score [-2 SD]) have a significantly increased risk for neurocognitive impairment (OR >2) while adjusting for gestational age, twin status, sex, and socioeconomic information. Conclusions: HC at birth and HC dZ-score between birth and hospital discharge are synergistically associated to neurodevelopmental outcome at 2 years of corrected age, in a population-based prospective cohort of preterm infants born ≤34 weeks of gestation.

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Section: Introductionmentioning

confidence: 48%

Fetal and Postnatal Head Circumference Growth: Synergetic Factors for Neurodevelopmental Outcome at 2 Years of Age for Preterm Infants

Sicard¹,

Nusinovici

Hanf

et al. 2017

Neonatology

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“…10,11 Following Hack's original work 12,13 associating HC at 8 months with later IQ, more recent preterm cohorts have reproduced similar findings correlating head growth from birth to discharge with improved neurodevelopmental outcomes at 2 years 9,31,32 and 4 to 6 years. [32][33][34][35] A similar relationship between HC at 9 months and later cognitive function has also been described in term infant populations. 36 These observational studies consistently demonstrate the relationship between head growth in infancy and later neurodevelopment and suggest that the head growth in the period immediately after birth is a useful surrogate for important longterm outcomes.…”

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confidence: 63%

Postnatal Head Growth in Preterm Infants: A Randomized Controlled Parenteral Nutrition Study

et al. 2014

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WHAT'S KNOWN ON THIS SUBJECT: Preterm infants dependent on parenteral nutrition are vulnerable to deficits in early postnatal nutritional intake. This coincides with a period of suboptimal head growth. Observational studies indicate that poor nutritional intake is associated with suboptimal head growth and neurodevelopmental outcome. WHAT THIS STUDY ADDS:This study provides randomized controlled trial evidence that head growth failure in the first 4 weeks of life can be ameliorated with early nutritional intervention. Early macronutrient intake can be enhanced by optimizing a standardized, concentrated neonatal parenteral nutrition regimen. abstract BACKGROUND: Early postnatal head growth failure is well recognized in very preterm infants (VPIs). This coincides with the characteristic nutritional deficits that occur in these parenteral nutrition (PN) dependent infants in the first month of life. Head circumference (HC) is correlated with brain volume and later neurodevelopmental outcome. We hypothesized that a Standardized, Concentrated With Added Macronutrients Parenteral (SCAMP) nutrition regimen would improve early head growth. The aim was to compare the change in HC (DHC) and HC SD score (DSDS) achieved at day 28 in VPIs randomly assigned to receive SCAMP nutrition or a control standardized, concentrated PN regimen. METHODS:Control PN (10% glucose, 2.8 g/kg per day protein/lipid) was started within 6 hours of birth. VPIs (birth weight ,1200 g; gestation ,29 weeks) were randomly assigned to either start SCAMP (12% glucose, 3.8 g/kg per day protein/lipid) or remain on the control regimen. HC was measured weekly. Actual daily nutritional intake data were collected for days 1 to 28.RESULTS: There were no differences in demographic data between SCAMP (n = 74) and control (n = 76) groups. Comparing cumulative 28-day intakes, the SCAMP group received 11% more protein and 7% more energy. The SCAMP group had a greater DHC at 28 days (P , .001). The difference between the means (95% confidence interval) for DHC was 5 mm (2 to 8), and DSDS was 0.37 (0.17 to 0.58). HC differences are still apparent at 36 weeks' corrected gestational age. Dr Morgan developed the original concept and designed the study, ensured regulatory approvals, performed some study measurements, data collection and collation, coordinated data analysis, and drafted the initial manuscript; Mr McGowan performed most of the study measurements, data collection, and collation, contributed to data analysis and made study design modifications; Mr Herwitker was involved with study design and regulatory approval, overseeing study PN manufacture, and some data collation; Ms Hart provided the medical statistical support at the design, monitoring, and analytical stages of the study; Dr Turner was involved in study design and data analysis; and all authors approved the final manuscript as submitted. CONCLUSIONS:This trial has been registered with the ISRCTN Register (http:// isrctn.org) (identifier ISRCTN76597892 Improved survival of very preterm infants (VPIs) ha...

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“…Even though faster growth in infancy and childhood has been shown to benefit neurodevelopment in those born very preterm (<32 weeks) (9)(10)(11)(12), early preterm (<33 weeks) (13), preterm (14), and preterm with extremely low (<1000g) (15)(16)(17)(18) or very low (<1500g) (9,10,(19)(20)(21)(22) birth weight, in some, though not in all studies (23-25), it still remains unknown if faster early growth also benefits neurodevelopment in those born late-preterm. Accordingly, we examined if growth after late-preterm birth predicts neurocognitive functioning, academic performance, or mental health in individuals who were born latepreterm, and who participated in follow-up examinations at 5 and 20 months of corrected age (CA) and 56 months and 25 years of age.…”

Section: Introductionmentioning

confidence: 99%

Growth after late-preterm birth and adult cognitive, academic, and mental health outcomes

et al. 2017

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Postnatal growth of preterm born children ≤750g at birth

Cited by 52 publications

References 45 publications

Fetal and Postnatal Head Circumference Growth: Synergetic Factors for Neurodevelopmental Outcome at 2 Years of Age for Preterm Infants

Fetal and Postnatal Head Circumference Growth: Synergetic Factors for Neurodevelopmental Outcome at 2 Years of Age for Preterm Infants

Postnatal Head Growth in Preterm Infants: A Randomized Controlled Parenteral Nutrition Study

Growth after late-preterm birth and adult cognitive, academic, and mental health outcomes

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