Postnatal developmental Histomorphological and histochemical study of the pancreas in the domestic cat (Felis Catus).

Abstract

Objective: The present study was conducted to investigate the histomorphological and histochemical postnatal developmental changes established in the pancreas of the domestic cats. Methodology: the study conducted on three different postnatal ages that were one week (suckling kittens), 4-6 weeks (weaned immature cats) and adult of one year and up cats. Macromorphometric measurements of pancreas were conducted and listed in tables. Histological sections prepared and stained by general and special stains. Results: Gross findings revealed that the pancreas of cat was of compact type, of two lobes connected by small central part. Critical macromorphometric changes observed at 4 weeks aged cats. The organ drains the pancreatic secretion toward the duodenum via main pancreatic duct. Exocrine portion more developed after birth than the endocrine portion; however both were faced developmental changes. The parenchyma provided with well duct system even in kitten. Ducts were surrounded by smooth muscle fibers invested in the connective tissue. Endocrine portion showed in kittens predominant α cells. Critical changes occurred at 4 weeks of age caused an increase of the number of ß cells so that the ratio of α / ß was changed. In adult cats the percentage of ß was predominant. In all studied ages of cats, the findings revealed the presence of well developed autonomic innervations represented by the presence of large autonomic ganglion, intramural ganglia and large sized Pacinian corpuscles. Conclusions: It could be concluded that pancreas was not fully developed at birth and weaning period caused critical development.Copy Right, IJAR, 2017,. All rights reserved. …………………………………………………………………………………………………….... Significance of the study:The significance of the current findings can be categorized into two criteria. First of all, it was first investigation focused on the development of the pancreas postnatally of the domestic cats in veterinary field. The second criteria, as the pancreas of the cats showed morphological similarities to those of human especially the presence of Pacinian ISSN: 2320-5407Int. J. Adv. Res. 5(2), 55-71 56 corpuscles, presence and distribution of α and β cells in the islets of Langerhans, such findings will be beneficial for public health and animal health and welfare.

Comparative Morphohistological Study of Pancreatic Ducts in Rabbits and Guinea Pigs

“…The presence of minor pancreatic duct and absence of the major one in both studied rabbits and guinea pigs was in agreement with what was found in the pancreas of pigs and Ox [6]. Whereas differently, in some small and laboratory animal species such as mice [7], hamster [8] and cat [9], dogs [10,11], the major pancreatic duct was present as the only and the main pancreatic duct andabsence totally minor pancreatic duct or even the second accessory duct. In the rat, the duct system of the pancreas had a great variation because in the past decade, [12] observed anterior and posterior pancreatic ducts instead of the major pancreatic ducts.…”

Histomorphological and carbohydrate histochemical study of the pancreas in native ducks (Anas Platyrhynchos)

“…The intralobular and interlobular ducts are made up of two distinctive tissues: a columnar epithelium with goblet cells that line the ducts and is bordered by connective tissue; and simple columnar epithelium tissue that lines the main duct lines. (22) found that all portions of the pancreas's duct system lack goblet cells in their lining epithelium at all analyzed ages.…”

Morphological Study of The Pancreas and Duodenum in Adult Guinea Pigs (Cavia porcellus)

“…The organ was clearly observed at the right side of the abdominal cavity and was held together with the pancreas to the dorsal wall of the abdominal cavity by a fold of the duodenal mesentery. Accordingly, these morphological findings being disagreement with those found in the domestic cat (17) and rabbit (31) where they referred that the duodenum was Table 2. Micromorphometric measurements of weights and lengths of descending and ascending duodenum in adult female and male guinea pigs (Cavia porcellus) 7…”

“…The pancreas found of compact type in the adult studied guinea pigs which was dissimilar to other animal species that were possessed of mesenteric or diffused type of pancreas such as Wister and Sprague-Dawley rats (14) and in the domestic rabbit (15). In another aspect, the compact type of pancreas of guinea pigs was similarly recorded in humans and animals such as monkeys, minipigs, dogs, cats and hamsters (16,17,18). The gross current findings showed three lobes in adult guinea pig pancreas.…”

“…Obviously, in some animal species such as pig and ox, the right pancreatic lobe appeared closely related to the descending duodenum (22) and such observation was as same as in the current studied guinea pig, whereas, oppositely in the rabbit's pancreas the duodenal or right lobe observed closely adherent to the ascending limb of the duodenum (15).The body of the pancreas represented the connecting part between right and left lobes with the absence of distinct demarcation between these lobes. However, it was well characterized by the passage of the portal vein through it which was considered a good vessel marker in the previous researches (23,24). Current findings detected the presence of minor pancreatic duct only and the absence of the major pancreatic duct in the pancreas of adult male and female guinea pigs.…”