Postnatal Development of Bile Secretory Physiology in the Dog
Nicola Tavoloni,
Mary Jane T. Jones,
Paul D. Berk
Abstract:To determine whether bile formation in the dog is an immature process at birth, several determinants of bile secretion were studied in anesthetized, bile duct‐cannulated puppies of 0–42 days of age and adult dogs. Basal canalicular bile flow rate, estimated by 14C‐erythritol biliary clearance, averaged 0.182 μl/min/g liver in 0–3 day‐old puppies and increased to 0.324 and 0.461 μl/min/g in puppies 7–21 and 28–42 days of age, respectively. The latter two values were not significantly different from that observe… Show more
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