Postmastectomy Electron-Beam-Rotation Irradiation in Locally Advanced Breast Cancer

Abstract

In high-risk breast cancer patients postmastectomy irradiation with the electron-beam-rotation technique is an effective therapy, resulting in a 5-year local failure rate of 8%. Intensified local therapy needs further investigation in subgroups of patients with additional risk factors.

Verifikation und Anwendungen des voxelbasierten Monte-Carlo-(VMC++-)Elektronen-Dosismoduls von Oncentra™ MasterPlan

“…Es ist zu erwarten, dass insbesondere spezielle Bestrahlungstechniken [12,22], z.B. Rotationsbestrahlung mit Elektronen [13], von der präzisen Dosisberechnung profitieren sowie Feldanschlüsse zwischen Photonen-und Elektronenfeldern besser optimiert und Lungenbelastungen besser evaluiert werden können. Figures 4a and 4b.…”

In Vivo Verification of Electron Beam Energy by Patient Exit Dose and Optical Density of Portal Films

“…The use of electron beams in radiotherapy offers the advantage of a steep decrease of dose beyond its maximum, thereby sparing organs at risk that are located deeper than the target volume [9,10,14,19]. This dose fall-off depends on the energy of the electron beam [2,16,17,21,23].…”

Postmastectomy Radiotherapy of the Chest Wall

“…It was thought that electron-rotation irradiation in patients with homogeneous chest wall thickness, in mediolateral and craniocaudal dimension, provides sufficient dose to the chest wall, skin and underlying soft tissue, especially in tumors with lymphangiosis cutis [15,18]. Moreover, the scattered dose to the lung and heart could be kept low, by choosing electron energies between 4-12 MeV, depending on minimal chest wall thickness, which, in contrast, might partly spare deep intercostal spaces.…”