Postinhibitory excitation in motoneurons can be facilitated by hyperpolarization-activated inward currents: a simulation study
Laura Schmid,
Thomas Klotz,
Oliver Röhrle
et al.
Abstract:Postinhibitory excitation is a transient overshoot of a neuron’s baseline firing rate following an inhibitory stimulus and can be observedin vivoin human motoneurons. However, the biophysical origin of this phenomenon is still unknown and both reflex pathways and intrinsic motoneuron properties have been proposed. We hypothesized that postinhibitory excitation in motoneurons can be facilitated by hyperpolarization-activated inward currents (h-currents). Using an electrical circuit model we investigated how h-c… Show more
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