Posterolateral Fusion versus Transforaminal Lumbar Interbody Fusion in the Surgical Treatment of Low-Grade Isthmic Spondylolisthesis

Abstract

Background Data: Surgical treatment of isthmic spondylolisthesis includes decompression, fixation and bone fusion. There are different suitable techniques for fusion as (PLF) posterolateral fusion (TLIF) transforaminal lumbar interbody fusion, (PLIF) posterior lumbar interbody fusion, (ALIF) anterior lumbar interbody fusion but still controversy remains about the best technique. Purpose: To evaluate and compare the surgical results of PLF versus TLIF with pedicle screw fixation in treatment of low-grade isthmic spondylolisthesis. Study design: A prospective randomized clinical case series. Patients and methods: This study included 40 patients with low grade isthmic spondylolisthesis. All patients were surgically treated by posterior decompression, transpedicular screw fixation and bone fusion. Patients were divided into two equal groups according to the type of bone fusion. Group A included 20 patients treated with PLF, and Group B included another 20 patients and were treated with TLIF. We used Visual Analogue Scale (VAS) for assess pain and the Oswestry Disability Index (ODI) to evaluate the functional outcome among our patients. Patients have been followed up for at least six months after surgery. Results: The improvement of VAS of back pain was significantly greater in group B (TLIF) (change 5.25±1.55) than in group A (PLF) (change, 4.4±1.14) (P<0.05). There was no significant difference in improvement of ODI in both groups. Patients with BMI³30 showed that group B experienced more clinical improvement than in group A in the VAS (P=0.021). The operative time in group B (185±24.5 min) was significantly longer than in group A (123.3±19.6 min) (P=0.034). Intraoperative blood loss in group B (584±192.1 ml) was significantly greater than in group A (417±182.4 ml) (P=0.008). The complication rate in group A (30%) was significantly less than in group B (55%) (P= 0.032) but broken screws (hardware failure) were more common in group A (20%) than in group B (0.0%) (P=0.01). The fusion rate in group B (95%) was higher than in group A (75%). Conclusion: Our data suggest that although TLIF is better than PLF in achievement of successful bone fusion and improvement of patient's symptoms (back pain and sciatica), PLF still considered simple technique with minimal operative blood loss, less operative time and little complications. (2018ESJ162)

Clinical Outcome Assessment following Open Reduction and Instrumented Posterior Interbody Fusion of Adult Single-Level Lumbar Spondylolisthesis

“…The superiority of one technique over another is still a matter of controversy in the current literature. 2,10 Spondylolisthesis could be either reduced and/or fused in situ with no definitive evidence existing for better functional outcome with one modality over the other. However, various reduction techniques have been described in the literature if reduction of spondylolisthesis is desired to benefit the overall sagittal balance of the patient.…”

Outcome of Transforaminal Lumbar Interbody Fusion versus Posterolateral Lumbar Fusion with Instrumentation in Treatment of Degenerative Lumbar Disorders

“…al. in 2018, where they recorded 123.25 minutes of mean operative time for PLF patients and 185 minutes for TLIF patients 8. …”