Posterior Vitreous Structures Evaluated by Swept-source Optical Coherence Tomography with En Face Imaging

Abstract

PurposeTo evaluate posterior vitreous structures using swept-source (SS) optical coherence tomography (OCT) with en face imaging.MethodsWe retrospectively reviewed OCT images of healthy individuals who did not have intra-ocular disease. We obtained high-definition horizontal and vertical line scans crossing the fovea and 3D scans using SS-OCT, with the 3D scan centered between the fovea and the optic-nerve head. An enhanced vitreous visualization function was used to highlight vitreous structures. En face mode was used to measure the area of Martegiani (AM) and bursa premacularis (BP). We performed all measurements using a built-in function of the viewing software.ResultsWe enrolled 24 eyes from 12 healthy individuals. The mean patient age was 28.7 ± 4.6 years (range, 24 to 39 years). The mean AM and BP areas were 5.73 ± 0.88 and 18.76 ± 6.95 mm2, respectively. In en face imaging, AM shape was most frequently a vertical oval (18 / 22, 81.8%), while the predominant BP shape was round (16 / 20, 80.0%). AM was in contact with the optic disc, either at the temporal-disc margin (13 eyes, 59.1%) or the nasal optic-disc margin (9 eyes, 40.9%).ConclusionsPosterior vitreous structures, such as AM and BP, were readily visualized using en face imaging with SS-OCT. Investigating normal vitreous configuration might help in understanding changes in vitreous structures associated with retinal pathology.

Swept Source Optical Coherence Tomography Assessment of Bursa Premacularis in Healthy Eyes

“…In our sample, we identified a new morphological pattern called boomerang shape, as well as the preexisting patterns already described by Park et al [ 18 ] such as the boat, wedge, and irregular ones.…”

“…A progressive temporal extension of BPM has been previously observed during childhood growth. In addition, a previous work [ 18 ] has reported that BPM seems to move anteriorly with increased posterior vitreous detachment. The latter condition was not present in our cohort of healthy and young subjects suggesting a more posterior and horizontal position of BPM.…”

An en face swept source optical coherence tomography study of the vitreous in eyes with anterior uveitis

“…The in vivo assessment of these structures has recently become feasible with the advent of OCT (Hwang et al 2020), but even then, this analysis has been limited by resolution and scan volume. With the advent of SS-OCT technology characterized by a faster acquisition procedure and unprecedented resolution, volume and sampling density, the vitreous analysis is nowadays easily achieved (Park et al 2018;She et al 2019;Leong et al 2020).…”

“…With the development of swept source optical coherence tomography (SS‐OCT) that has an axial resolution of 8 mm and lateral resolution of 20 mm with an approximate imaging depth of 2.6 mm, many investigators (Park et al. 2018; She et al. 2019) confirmed the presence of the PB, whose anterior border is vitreous gel and the posterior border is composed of a thin layer of the vitreous cortex attached to the retina.…”

Incomplete posterior vitreous detachment despite vitrectomy with silicone oil tamponade

“…It may not be well seen barely by ophthalmoscopy examination, but emulsified SO droplets act as the agent highlighting out the two Latin American Journal of Ophthalmology natural retro-hyaloid spaces. [2] e emulsified SO droplets float according to gravity, but were entrapped over the preoptic disc and the pre-macular bursa, giving the funny double inverse hypopyon-like pattern over the posterior segment.…”