Posterior mediastinal neurilemmoma accompanied by intrapulmonary sequestration in the left lower lobe

Yang, Yue; Hua, Xin; Xu, Bao-Cen; Zhang, Le-Ning; Zhao, Wei

doi:10.1097/md.0000000000016582

Cited by 4 publications

(3 citation statements)

References 7 publications

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“…It is estimated that 9% of all schwannomas occur in the mediastinum. [10] Fifty percent of neurogenic tumors of the mediastinum are schwannomas. [3] In our series, schwannomas represented 5% of all soft tissue tumors of the mediastinum.…”

Section: Discussionmentioning

confidence: 99%

Retrospective Analysis of the Clinical and Image Presentation of Eight Primary Benign Mediastinal Schwannomas

Sandoval-Macias¹,

Ortiz-Sanchez²,

Remirez-Castellanos³

et al. 2021

Preprint

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Objective: Mediastinal schwannomas sometimes can be confused with other neoplasms in the initial radiological studies, especially when there is a history of cancer in another site and that require a more accurate analysis by computed tomography (CT) or even magnetic resonance (MRI). Our study was aimed to perform a retrospective analysis of the clinical and imaging features in a series of patients with mediastinal schwannomas that were confirmed by histology and immunohistochemistry.Results: We found eight patients, five man and three women with an average age of 51 years. The main signs and symptoms at time of diagnosis were chest pain, dyspnea, cough and dysphagia. CT showed that the tumor was located in the posterior compartment of the chest in 7/8 cases. Tumors >10 cm were more heterogeneous and showed cystic changes. All cases underwent posterolateral thoracotomy and radiological follow-up showed no evidence of recurrence. Histological analysis was the gold standard to confirm diagnosis in addition to at least one neurogenic IHC marker. In conclusion, mediastinal schwannomas are benign encapsulated tumors. By CT, schwannomas >10 cm showed cystic degeneration more frequently. Posterolateral thoracotomy allows complete resection and is considered the surgical approach of choice.

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Section: Discussionmentioning

confidence: 99%

Retrospective Analysis of the Clinical and Image Presentation of Eight Primary Benign Mediastinal Schwannomas

Sandoval-Macias¹,

Ortiz-Sanchez²,

Remirez-Castellanos³

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…Less than 9% of all schwannomas occur in the mediastinum [ 3 , 4 , 11 ]. In their epidemiological analysis of 1005 primary mediastinal neoplasm cases, Szolkowska et al [ 4 ], found that only 5% of mediastinal neoplasms correspond to schwannomas.…”

Section: Main Textmentioning

confidence: 99%

Retrospective analysis of the clinical presentation and imaging of eight primary benign mediastinal schwannomas

et al. 2021

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Objective Mediastinal schwannomas are sometimes confused with other neoplasms during initial radiological studies, especially when there is a history of cancer in another area. In these cases, a more accurate analysis using computed tomography (CT) or even magnetic resonance (MRI) is required. Our study aimed to perform a retrospective analysis of the clinical and imaging features for a series of patients with mediastinal schwannomas that were confirmed by histology and immunohistochemistry. Results We found eight patients, five men and three women, with an average age of 51 years for this study. The main signs and symptoms at diagnosis were chest pain, dyspnea, cough, and dysphagia. CT showed that the tumor was located in the posterior compartment of the chest in 7/8 cases. Tumors > 10 cm were more heterogeneous and showed cystic changes. All patients underwent posterolateral thoracotomy, and radiological follow-up showed no evidence of recurrence. Histological analysis was considered the gold standard to confirm diagnosis, along with at least one neurogenic IHC marker. In conclusion, mediastinal schwannomas are benign encapsulated tumors. According to CT, schwannomas > 10 cm show cystic degeneration more frequently. Posterolateral thoracotomy allows complete resection and is considered the surgical approach of choice.

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“…Most intrathoracic neurogenic tumours originate in the posterior mediastinum and only 5.4% are in the chest wall. 1 Approximately 95% of the pleural dependent tumours are malignant, most of which present as a product of metastasis. Needless to say, benign pleural tumours are very unusual and, among them, schwannoma is much less frequent.…”

Section: Introductionmentioning

confidence: 99%

Primary Pleural Schwannoma as Incidental Findings: An Unusual Case Report

2022

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Schwannomas are neurogenic, benign, slow growing tumours that originate in Schwann's intersecting fascicles of the peripheral nerves. This article reports the case of a previously healthy 51-year-old male, where a 9.0x6.5 cm (3.5x2.5 in) sized pleural mass was found after the patient presented a haemoglobin level of 3.2 g/dL in a blood smear at a routine check-up. The patient had no relevant medical, family, or psychosocial history and presented no relevant symptoms. After diagnosing and treating a chronic haemorrhoidal disease, the tumour was removed and studied. Demonstrating histopathological and immunohistochemical features of schwannoma, its uniqueness and rarity after successful management of the disease contributes to the medical literature as a histopathologic diagnostic standard and a therapeutic option for future cases of pleural schwannoma. Sharing the histopathologic features of schwannoma is not common, usually, the available case reports are lacking. The patient was able to recover fully and had no significant or severe complications associated with medical care.

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Posterior mediastinal neurilemmoma accompanied by intrapulmonary sequestration in the left lower lobe

Cited by 4 publications

References 7 publications

Retrospective Analysis of the Clinical and Image Presentation of Eight Primary Benign Mediastinal Schwannomas

Retrospective Analysis of the Clinical and Image Presentation of Eight Primary Benign Mediastinal Schwannomas

Retrospective analysis of the clinical presentation and imaging of eight primary benign mediastinal schwannomas

Primary Pleural Schwannoma as Incidental Findings: An Unusual Case Report

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