Posterior Lip Sclerectomy vs Trabeculectomy in West Indian Blacks

Wilson, M. Roy

doi:10.1001/archopht.1989.01070020682027

Cited by 20 publications

(6 citation statements)

References 16 publications

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“…In a review of 39 eyes (mean age 59.6 years) after fornix-based trabeculectomy, Shingleton et al [12] found a 49% success rate (IOP 20 mm Hg) without glaucoma medications, improving to 69% with medications, after a mean follow-up of 6.2 months; the mean IOP was 17 mm Hg, and most of the blebs were scarred (22/39, 56%). Wilson [13] prospectively studied 32 eyes (mean age 63.8 yrs) undergoing limbus-based trabeculectomy and reported a mean IOP of 16.1 mm Hg after a mean of 28.1 months, with 53% using no medications and 72% considered successes (IOP 20 mm Hg); 75% (24/ 32) had blebs that were either scarred, thick or localized.…”

Section: Discussionmentioning

confidence: 43%

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Trabeculectomy with Long-Term-Stored Mitomycin C in a West Indian Population

1998

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We investigated the outcome of trabeculectomy with stored mitomycin C (MMC) in a black Caribbean population on the island of Dominica. Ten eyes (9 patients) underwent trabeculectomy with MMC (0.5 mg/ml for 3–6 min) that had been stored for up to 17 months at 4 °C. The preoperative intraocular pressure of (mean ± SD) 32.8±7.5 mm Hg on 2.6 medications decreased to 9.5±3.2 mm Hg on 0.2 medications after a mean follow-up time of 14.2 months (range 7–25). Nine eyes did not receive medications postoperatively. Complications observed included bleb infection (1 eye) and late bleb leak (1 eye); 2 eyes developed cataract. Nine blebs had typical clinical features of blebs after trabeculectomy with adjunctive MMC. We conclude that long-term-stored MMC may be beneficial as adjunctive treatment in initial trabeculectomy in this population.

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Section: Discussionmentioning

confidence: 43%

“…Using the same criteria for success as Shingleton et al [12] and Wilson [13] (IOP 20 mm Hg), the success rate in this study was 100%.…”

Section: Discussionmentioning

confidence: 46%

Trabeculectomy with Long-Term-Stored Mitomycin C in a West Indian Population

1998

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“…'3-' [22][23][24][25][26][27][28][29][30][31][32][33][34][35][36] Although surgical success in black patients has been reported to be greater by some groups 32 3436 than others,' 1424 it is generally accepted that the success of glaucoma filtration surgery in black patients is not as high as with white patients. Comparisons made between studies can be misleading for various reasons such as varying criteria for success, diagnostic categories, follow up periods, and operating facilities or techniques.…”

Section: Discussionmentioning

confidence: 99%

Racial differences in the results of glaucoma filtration surgery: are racial differences in the conjunctival cell profile important?

Broadway

Grierson

Hitchings

1994

British Journal of Ophthalmology

117

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“…Although it remains unclear whether fewer goblet cells could incite a more exuberant healing response in blacks, further evaluation is warranted to understand the adverse effect of glaucoma medications on goblet cells in black and white patients. In fact, better results of trabeculectomy were seen in blacks when trabeculectomy was the primary procedure rather than secondary intervention after failure of medical therapy 43. In AGIS, black patients were also found to be on more glaucoma medications preoperatively than were white patients in both treatment sequences.…”

Section: Discussionmentioning

confidence: 99%

Surgical outcomes of the Ex-PRESS glaucoma filtration device in African American and white glaucoma patients

Salim¹,

Du²,

Boonyaleephan³

et al. 2012

OPTH

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PurposeTo compare the surgical outcomes of the Ex-PRESS glaucoma filtration device in African American and white glaucoma patients.DesignRetrospective comparative case series.MethodsThis was a comparative case series of 36 eyes of 36 African Americans and 43 eyes of 43 whites that underwent placement of the Ex-PRESS glaucoma filtration device under a partial-thickness scleral flap for uncontrolled glaucoma. All eyes received intraoperative mitomycin C. The primary outcome measures were intraocular pressure (IOP), number of postoperative glaucoma medications, and surgical success. Surgical success was defined as IOP between 5 and 18 mm Hg, with or without glaucoma medications, without further glaucoma surgery, or loss of light perception vision.ResultsAverage follow-up was 31.9 ± 9.8 (range, 14.6–47) months for African Americans and 30.7 ± 8.6 (range, 14.3–47) months for whites. At 33 months, surgical success was 80.0% in the African American group and 83.3% in the white group (P = 1.00). Reasons for surgical failure included increased IOP (3 eyes, 3.8%), persistent hypotony with maculopathy (1 eye, 1.3%), and further surgery (4 eyes, 5.06%). Compared with preoperative values, the mean postoperative IOP and number of glaucoma medications were significantly reduced in both groups, and no statistical difference was observed between the two groups at 33 months. Postoperative complications were similar in the two groups.ConclusionsSimilar surgical outcomes were observed in African American and white glaucoma patients after implantation of the Ex-PRESS glaucoma filtration device. This latest modification of glaucoma filtration surgery may be a better surgical option for African Americans given its potential advantages of no tissue removal, predictable outcomes related to consistent lumen size and controlled flow, fewer postoperative complications, and overall reduced inflammation.

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Posterior Lip Sclerectomy vs Trabeculectomy in West Indian Blacks

Cited by 20 publications

References 16 publications

Trabeculectomy with Long-Term-Stored Mitomycin C in a West Indian Population

Trabeculectomy with Long-Term-Stored Mitomycin C in a West Indian Population

Racial differences in the results of glaucoma filtration surgery: are racial differences in the conjunctival cell profile important?

Surgical outcomes of the Ex-PRESS glaucoma filtration device in African American and white glaucoma patients

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