Posterior fossa syndrome in a patient with an ornithine transcarbamylase deficiency

Nedermeijer, S.C.M.; Hout, J. van den; Geleijns, C.; Klerk, H. de; Catsman‐Berrevoets, Coriene E.

doi:10.1016/j.ejpn.2014.12.001

Cited by 5 publications

(1 citation statement)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We found one case of reported mutism related to a metabolic disorder (ornithine transcarbamylase deficiency). This X-linked urea cycle disorder results in neurotoxic hyperammonaemia with neurologic symptoms such as seizures, decreased consciousness and abnormal motor function [ 33 ]. In this reported case mutism lasted 4 days.…”

Section: Resultsmentioning

confidence: 99%

Cerebellar mutism syndrome of non-tumour surgical aetiology—a case report and literature review

et al. 2023

View full text Add to dashboard Cite

Cerebellar mutism syndrome (CMS) is a well-known complication of posterior fossa (PF) tumour surgery. CMS has previously been reported in cases of non-tumour surgical aetiology in a limited number of publications. We report a case of a 10-year-old girl who suffered a cerebellar haemorrhage and subsequent CMS following surgical treatment of a ruptured arteriovenous malformation (AVM) in the cerebellar vermis. The AVM was removed acutely through a transvermian access, and hydrocephalus was treated with temporary external drainage. In the postoperative period, she suffered diffuse vasospasms of the anterior cerebral circulation and had a permanent shunt placed for hydrocephalus. Her mutism resolved after 45 days but severe ataxia persisted. To our knowledge, this is the first reported case of CMS related to a vermian haemorrhagic stroke with postoperative diffuse vasospasms. Based on this case, we present a literature review on CMS of non-tumour surgical origin in children.

show abstract

Section: Resultsmentioning

confidence: 99%

Cerebellar mutism syndrome of non-tumour surgical aetiology—a case report and literature review

et al. 2023

View full text Add to dashboard Cite

show abstract

Consensus paper on post-operative pediatric cerebellar mutism syndrome: the Iceland Delphi results

et al. 2016

View full text Add to dashboard Cite

The consensus process was motivated by desire to further research and improve quality of life for pediatric brain tumor patients. The Delphi rounds identified relevant topics and established basic agreement, while face-to-face engagement helped resolve matters of conflict and refine terminology. The new definition is intended to provide a more solid foundation for future clinical and research work. It is thought as a consensus for moving forward and hopefully paves the way to developing a standard approach to this challenging problem with the advent of better scoring methods and ultimate goal of reducing the risk of CMS.

show abstract

Cerebellar mutism syndrome

Catsman‐Berrevoets

Patay

2018

Handbook of Clinical Neurology

View full text Add to dashboard Cite

Posterior fossa syndrome in a patient with an ornithine transcarbamylase deficiency

Cited by 5 publications

References 13 publications

Cerebellar mutism syndrome of non-tumour surgical aetiology—a case report and literature review

Cerebellar mutism syndrome of non-tumour surgical aetiology—a case report and literature review

Consensus paper on post-operative pediatric cerebellar mutism syndrome: the Iceland Delphi results

Cerebellar mutism syndrome

Contact Info

Product

Resources

About