Posterior Fossa Calcifying Pseudoneoplasm of the Neuraxis (CAPNON): Presentation of Three Surgical Cases

Domecq-Laplace, Lucila; Ruella, Mauro; Caffaratti, Guido; Villamil, Facundo; Monsalve, Martin; Alcorta, Santiago Condomí; Cervio, Andrés

doi:10.1016/j.wneu.2022.08.022

Cited by 1 publication

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“…In this study, 58 MA cases (93.55%;58/62) and 46 CAPNON cases (92%;46/50) were selected for surgery, particularly in high-risk areas. For instance, Lucila Domecq Laplace et al [ 27 ] reported three cases of CAPNON located in the posterior fossa with perilesional edema, and the vast majority were cured after total resection. However patients may experience recurrence because of incomplete evacuation [ 28 ], neoplastic malignancy [ 12 ], or coexisting with other malignant tumors [ 20 , 21 ].…”

Section: Discussionmentioning

confidence: 99%

Meningioangiomatosis Combined with Calcifying Pseudoneoplasms of Neuraxis

Sun

Cai

et al. 2023

Brain Sciences

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Meningioangiomatosis (MA) is a rare hamartomatous or meningovascular lesion involving the central nervous system, and is sometimes associated with intracranial meningiomas. Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare, slow-growing benign tumor-like lesions that can occur anywhere along the neuraxis. Here, we report a rare case of MA combined with CAPNON. A 31-year-old woman was admitted to our hospital because of a high-density mass in the left frontal lobe, detected by computed tomography (CT) during a physical examination. She had a 3-year history of obsessive–compulsive disorder. We describe the imaging, histopathological, and molecular characteristics of the patient. To our knowledge, this is the first report describing MA combined with CAPNON. We reviewed the literature on MA and CAPNON over the last decade and summarized the points for differential diagnosis and treatment. It is difficult to preoperatively distinguish between MA and CAPNON. However, this coexisting condition should be considered when intra-axial calcification lesions are observed on radiological imaging. Accurate diagnosis and appropriate treatment are likely to benefit this patient group.

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