Posterior Capsule Opacification in the Presence of an Intraocular Lens with a Sharp versus Rounded Optic Edge

Comparison of posterior capsule opacification between fellow eyes with two types of acrylic intraocular lens

“…In a recent study, we found that the degree of PCO is very slight in eyes with the Sensar IOL that has a sharp posterior edge. 11 The present study further clarified that PCO, as well as visual function, did not worsen in eyes with either the AcrySof or the Sensar IOL for up to 2 years after surgery.…”

“…11,[22][23][24][25][26] The AcrySof MA60AC has both sharp anterior and posterior edges, whereas the Sensar AR40e has a sharp posterior optic edge but a more round anterior optic edge. Because the degree of PCO was not different between eyes with these two different IOLs, the posterior optic edge must be more effective in preventing PCO than is the anterior optic edge.…”

“…This can be explained by the fact that a sharp capsular bend is formed along the posterior optic edge, which prevents invasion of PCO, because both the anterior and posterior capsules adhere after surgery at the anterior side of the optic. 11 Among the various hydrophobic acrylic IOLs, the chemical properties of the acrylic materials are different. For instance, it has been reported that the optic material of the AcrySof IOL tends to readily absorb intensely adhesive proteins, including fibronectin and vitronectin, which may lead to a strong adhesion of the optic to the lens capsule, and to subsequent prevention of PCO.…”

“…Contrast visual acuity and that measured in the presence of a glare source (glare visual acuity) were examined at 1 and 24 months after surgery using the Contrast Sensitivity Accurate Tester (CAT-2000; Menicon, Tokyo, Japan). 10,11 This device measures logMAR visual acuity using five contrast visual targets (100, 25, 10, 5, and 2.5%) under photopic and mesopic conditions. Measurement under photopic conditions was performed with chart lighting of 100 cd/mm 2 and that under mesopic conditions with chart lighting of 5 cd/mm 2 .…”

“…9,10 Our previous study did, in fact, demonstrate that PCO in eyes that received the AR40e IOL was very slight, which led to the maintenance of excellent visual function. 11 Thus, the AcrySof and Sensar IOLs were now considered to be two of the most preferred IOLs with regard to PCO.…”