Posterior Capsule Opacification after Cataract Surgery via Implantation with Hydrophobic Acrylic Lens Compared with Silicone Intraocular Lens: A Systematic Review and Meta-Analysis

Kwon, Ye Rin; Hwang, Yoo Na; Kim, Sung Min

doi:10.1155/2022/3570399

Cited by 11 publications

(13 citation statements)

References 51 publications

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“…In this study, PCO diagnosis was established after a median of 12 months, ranging from 8.2 months to 26.3 months after cataract extraction. Ayuningtyas et al [8] found that the duration of the PCO diagnosis was established since surgery with a median of 21 months with a range from one month to 34 months, while Kwon et al [17] found the duration of the PCO diagnosis was established in 16 months after surgery with a range of 6 to 18 months. It can be concluded that the results obtained in this study were following previous research.…”

Section: Resultsmentioning

confidence: 99%

Posterior Capsule Opacification (PCO) Cases at Lamongan Eye Clinic: Two Years of Retrospective Data

Suryani

Unari

2022

VSEHJ

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Introduction: Posterior capsular opacity (PCO) is the most common complication of cataract surgery. PCO is caused by the lens epithelial cells (LEC), which then proliferate in the capsular bag after surgery. Several complications can occur, such as increased intraocular pressure (IOP), cystoid macular edema (CME), retinal hemorrhage, retinal detachment, and implanted lens (IOL) damage. Capsule Nd:YAG laser is currently the standard procedure for treating PCO, with a success rate of 95%. Purpose: This study aimed to provide an overview of PCO incidence and the success rate of PCO handling in the eye clinic. Methods: This study was a retrospective observational study. Data was taken from medical records of patients diagnosed with PCO who came to the Lamongan Eye Clinic for two years (May 2018 to April 2020). Data regarding the profile of the subject was analyzed descriptively. The data distribution was tested using the Kolmogorov-Smirnov test. Results: From May 2018 to April 2020, 134 patients with PCO came to the Lamongan Eye Clinic. Mean pre-laser best-corrected visual acuity (BCVA) was 0.76 ± 0.44 (logMAR), post-laser was 0.40 ± 0.40 (logMAR). There was a significant difference in the mean refraction correction of the PCO patients before and after Nd:YAG laser capsulotomy, whereas the mean BCVA after undergoing YAG laser was higher than before. Mean pre-laser IOP was 15.00 ± 3.55 mmHg and post-laser was 14.20 ± 3.27 mmHg. The mean post-laser IOP was lower than the pre-laser IOP. The Nd:YAG laser capsulotomy significantly affected IOP. Conclusions: There is a statistically significant improvement in BCVA before and after capsulotomy. Capsulotomy had a significant effect on improving BCVA up to 7%; however, had no effect on IOP.

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Section: Resultsmentioning

confidence: 99%

Posterior Capsule Opacification (PCO) Cases at Lamongan Eye Clinic: Two Years of Retrospective Data

Suryani

Unari

2022

VSEHJ

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“…A meta-analysis study provided an assessment of 17 updated clinical studies of long-term complications and visual function after implantation of hydrophobic acrylic and silicone intraocular lenses from January 2000 to March 2021. The results of the analysis revealed a greater PCO value (Group 3: standardized mean difference: -0.59; CI: -0.90 to -0.28) and Nd: YAG capsulotomy rate (Group 3: hazard ratio (RR), 0.60; 95% CI, 0.40-0.89) for hydrophobic acrylic IOLs than silicone IOLs during long-term follow-up (≥6 years) [18].…”

Section: Major Clinical Findingsmentioning

confidence: 94%

Major clinical considerations of the use of hydrophobic intraocular lenses in patients with cataracts: a brief systematic review

Ferrari¹,

Murad²,

Moura³

et al. 2022

MedNEXT

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Introduction: Every year about 1 to 2 million people become blind and the number of blind people is predicted to reach 90 million in 2020. A cataract is the biggest cause of blindness in the world, except in developed countries. It accounts for 47.8% of the world's cases of blindness. A cataract is a name given to any opacity of the lens, which does not necessarily affect vision, with phacoemulsification being the main choice of treatment, which consists of a posterior aspiration of the emulsified material. Objective: The objective of this study was to evaluate, through a systematic review, the visual acuity, with less recourse to correction, in patients undergoing phacoemulsification with bilateral implants of hydrophobic lenses. Methods: The systematic review rules of the PRISMA Platform were followed. The literature search was carried out from July to August 2022 in Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. Scientific articles from the last 3 years were selected. The quality of the studies was based on the GRADE instrument. The risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 23 articles were included in this study, with 6 articles being from the main current clinical studies on the use of intraocular lenses. Both PCO value and Nd: YAG capsulotomy rates were higher in the hydrophobic acrylic IOL group than in the long-term use silicone (intraocular lens) IOL group (more than 6 years) after implantation. This study indicates excellent postoperative visual acuity and refractive results in the eyes following implantation of the EyeCee® One. This is accompanied by a very little risk of intraoperative and postoperative complications. Furthermore, the Aktis SP IOL is a safe, effective, and stable lens that can be inserted through a 2.2 mm incision with satisfactory visual and refractive results, even in the late postoperative period. Therefore, by analyzing the histopathological composition of PCO using LECs, more information can be gained about the characteristics of IOLs that are important for biocompatibility. Finally, patients implanted with trifocal IOLs showed a significant improvement in visual acuity at different distances, providing broad absolute and relative depth of field values, with good patient satisfaction rates.

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“…Posterior capsular opacification (PCO) is a common long-term complication that develops after cataract surgery and causes findings such as decreased visual acuity, photophobia, and glare [1][2][3]. The incidence of PCO after cataract surgery has been reported to vary between 2.5% and 50% [4].…”

Section: Introductionmentioning

confidence: 99%

“…PCO occurrence may depend on patient-related factors, the surgical technique applied, or the characteristics of the intraocular lens (IOL) implanted [2][3][4][5]. Not only the material of IOL, but also its edge profile and localization, are important in the formation of PCO [4,5].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Nd:YAG laser capsulotomy results in patients who underwent cataract extraction and intraocular lens implantation with the endocapsular phacoemulsification method

Yetkin

2023

J Surg Med

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Background/Aim: Posterior capsular opacification (PCO) is a common complication that develops after cataract surgery, and it can be treated neodymium-doped yttrium aluminum garnet (Nd:YAG) laser capsulotomy. In this study, we aimed to investigate the effects of different intraocular lenses (IOLs) on the development of posterior capsule opacification (PCO), to determine the time between surgery and Nd:YAG laser capsulotomy, and to evaluate the efficacy, effectiveness, and complications of capsulotomy in patients who underwent cataract surgery with the phacoemulsification method and subsequently developed PCO. Methods: The cohort study included one eye of each of 153 cases (63 males, 90 females) who underwent cataract surgery with the phacoemulsification method in our clinic from August 1, 2006, through August 1, 2008, and subsequently developed PCO. According to the type of IOL implanted, the cases were divided into three groups: polymethylmethacrylate IOL (Group 1), hydrophilic acrylic IOL (Group 2), and hydrophobic acrylic IOL (Group 3). The control examinations of the patients who underwent Nd:YAG laser capsulotomy were undertaken before capsulotomy and at the first week, first month, and third month after capsulotomy. Results: Visual acuity improvement was detected in 96.7% of the 153 cases. It was determined that 9.1% of the cases had an intraocular pressure (IOP) increase of more than 5 mmHg at the third hour after capsulotomy and approached baseline values at the end of 1 week. The mean total energy used in all the cases was 37.20 (14.70) mjl. The mean total energy used in 14 patients with an IOP elevation of above 5 mmHg was 71.07 (10.59) mjl. Nd:YAG laser capsulotomy was performed at an average of 6.29 (4.91) months in Group 1, 7.81 (4.35) months in Group 2, and 17.7 (12.35) months in Group 3. After capsulotomy, clinically significant cystoid macular edema was observed in 1.9% of the cases, IOL damage in 3.9%, and vitreous hemorrhage in 0.6%. Conclusion: In this study, the incidence of PCO development was found to be lower in the patients who underwent hydrophobic acrylic IOL implantation; therefore, this type of lens should be preferred for implantation. Although Nd:YAG laser capsulotomy is an outpatient treatment method that can be applied quickly and can increase visual acuity, it can also lead to complications. To eliminate most of these complications, it would be beneficial to minimize the energy used during the laser procedure.

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Posterior Capsule Opacification after Cataract Surgery via Implantation with Hydrophobic Acrylic Lens Compared with Silicone Intraocular Lens: A Systematic Review and Meta-Analysis

Cited by 11 publications

References 51 publications

Posterior Capsule Opacification (PCO) Cases at Lamongan Eye Clinic: Two Years of Retrospective Data

Posterior Capsule Opacification (PCO) Cases at Lamongan Eye Clinic: Two Years of Retrospective Data

Major clinical considerations of the use of hydrophobic intraocular lenses in patients with cataracts: a brief systematic review

Evaluation of Nd:YAG laser capsulotomy results in patients who underwent cataract extraction and intraocular lens implantation with the endocapsular phacoemulsification method

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