Post-vaccination cases of COVID-19 among healthcare workers at Siloam Teaching Hospital, Indonesia

Abstract

Background Healthcare workers (HCWs) compared to the general population are at an increased risk of exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease-19 (COVID-19). Therefore, they are given priority for the COVID-19 vaccine in the national COVID-19 vaccination campaign in Indonesia. However, when the daily new COVID-19 cases are still high, and the data regarding the vaccine’s efficacy in healthcare settings remains unavailable, the vaccinated HCWs still likely to get COVID-19 infection and at risk for further transmission. Objective To identify COVID-19 cases among vaccinated HCWs at Siloam Teaching Hospital, Indonesia, via active and passive surveillance conducted by the hospital’s COVID-19 infection prevention and control unit Results Among 1,040 HCWs who have received the first and second vaccination, 13 (1.25%) HCWs were positive for SARS-CoV-2 RNA detection by reverse-transcriptase polymerase chain reaction (RT-PCR) from 2-11 days (median five days) after the second vaccination. Conclusion The early laboratory-confirmed COVID-19 among post-vaccinated HCWs indicates that HCWs are still at risk to acquire COVID-19 disease during the vaccination campaign. Therefore, the presence of symptoms after vaccination cannot be considered as vaccine-related symptoms, and regular COVID-19 testing should be conducted among HCWs.

SARS-CoV-2 Breakthrough Infections among the Healthcare Workers Post-Vaccination with ChAdOx1 nCoV-19 Vaccine in the South Indian State of Kerala

“…The symptomatic profile of the infected vaccinated HCWs was found similar to that study from Siloam Teaching Hospital, Indonesia [16]. Nurses (43.75%) and the staffs with more positive patient contacts (68.75%) were more infected among the vaccinated samples, which agree with the fact that more infection control practices have to be followed in the hospital settings [20].…”

“…Comparison with other studies is mentioned in Table 4. In our study, the median days between the second dose and being tested positive for SARS-CoV-2 was 65 days which is much longer than reported in all the previous studies, which ranged from 5 days or 47 days [9,12,15,16]. Also, none of the vaccinated HCWs who tested positive for SARS-CoV-2 were hospitalized, and there were no deaths, which in turn proves that vaccination reduces hospitalization by 100% which is more than the results observed in a study conducted in Scotland (88%) [18] and England (43%) [19].…”

Attitudes of Parents with Regard to Vaccination of Children against COVID-19 in Poland. A Nationwide Online Survey

“…Nowadays, the recommendation has been verified and vaccination is recommended for each child aged 12–15 years in a single-dose schedule [ 42 ]. While COVID-19 vaccinations have been successful in protecting against severity and death among adults at risk (the elderly and chronic patients), these benefits may be less marked in children [ 43 , 44 ]. Firstly, children are far less likely to suffer from severe COVID-19 (e.g., the risk of hospitalization and death in the UK has been estimated at 2 per million cases) and far less likely to develop long COVID-19 syndrome [ 45 , 46 ].…”

Sveikatos Priežiūros Organizacijų Darbuotojų Nusiteikimas Skiepytis Covid-19 Vakcina: Sisteminė Literatūros Apžvalga Ir Metaanalizė

“…Atskira problema -infekuotumas ar susirgimas Covid-19 po vakcinacijos (pasitaiko dažniau) ar po buvusio SPO darbuotojų infekuotumo ar ligos (pasitaiko rečiau). Pasiskiepiję Covid-19 vakcina SPO darbuotojai gali būti potencialūs viruso perdavėjai, todėl jie turi pastoviai testuotis ir dėvėti asmens apsaugos priemones [70][71][72]. Tuo labiau, kad apie trečdalis infekuotų pacientų, taip pat ir medikų, nejaučia simptomų [73].…”

“…Ir nesiskiepiję Covid-19 vakcina, ir pasiskiepiję ar persirgę Covid -19 liga SPO darbuotojai yra potencialūs viruso platintojai tarp kolegų, pacientų ir lankytojų [55,74]. Potencialūs Covid-19 viruso platintojai, ypač nesiskiepiję, yra kolegijų ir universitetų studentai, atliekantys praktiką, dėl didelio jų judumo bei kontaktų SPO viduje ir išorėje [70][71][72][73][74][75][76]. Persirgę ar galimai persirgę Covid-19 liga ir dirbantys su Covid-19 pacientais medikai labiau linkę nesiskiepyti.…”