Abstract:Background: Excessive exposure to club drug (GHB) would cause cognitive dysfunction in which impaired hippocampal Ca 2+-mediated neuroplasticity may correlate with this deficiency. However, the potential changes of in vivo Ca 2 + together with molecular machinery engaged in GHB-induced cognitive dysfunction has never been reported. Objective: This study aims to determine these changes in bioenergetic level through ionic imaging, spectrometric, biochemical, morphological, as well as behavioral approaches. Mater… Show more
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