“…Cholesterol crystals are found occasionally in synovial effusions from patients with rheumatoid arthritis (23), ankylosing spondylitis (23), bursitis (23, 24), and osteoarthritis (25). Although most cholesterol crystals are flat, rectangular, and rhomboid, and resemble broad plates with a notched corner, needle forms can also be seen (25–27), which can lead to the false diagnosis of gout. Neutral lipids can also form birefringent crystals upon drying (28), which probably explains the initial confusion about the appearance of the aspirate on the dried slide.…”