Post-Transurethral Resection of Bladder Tumor Bladder Perforation Resulting in Mitomycin C Extravasation, Pudendal Neuralgia, and Ureterohydronephrosis

Should continuous bladder irrigation be recommended when single instillation of intravesical chemotherapy cannot be used after transurethral resection in low-risk non-muscle invasive bladder cancer?

“…Possible reasons for the lack of wide adoption of SI could be related with urologist issues (Some believe that decreasing low-grade bladder cancer recurrences is not clinically important) or health system issues (such as increase in costs, insufficient training and inexperience in handling chemotherapeutic agents among nursing staff), pharmacy logistics, uncertainty of malignancy and tumor invasion at the time of TURBT, suspected bladder perforation with possible serious side effects [ 9 ]. Even most complications related to Mitomycin C (MMC) extravasation are local and mild, bladder necrosis, pudendal neuritis or ureterohydronephrosis could potentially occur [ 10 ].…”