Post‐Transplantation Immunoadsorption Can Be Withheld in <scp>ABO</scp>‐Incompatible Kidney Transplant Recipients

Weerd, Annelies E. de; Agteren, Madelon van; IJzermans, Jan N.M.; Weimar, Willem; Betjes, Michiel G. H.

doi:10.1111/1744-9987.12316

Cited by 3 publications

(2 citation statements)

References 28 publications

(36 reference statements)

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“…. Recent evidence has shown no significant differences in transplant outcomes after abandoning routine post‐op antibody removal: a notable distinction from Tyden's study protocol . We also do not routinely use post‐op apheresis and reserve it only for cases with a significant titer rebound with acute graft dysfunction cases only.…”

Section: Discussionmentioning

confidence: 85%

Pediatric ABO‐incompatible kidney transplantation: Evolving with the advancing apheresis technology: A single‐center experience

Sethi

Bansal

Wadhwani

et al. 2018

Pediatric Transplantation

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Recent literature has endorsed favorable outcomes following ABOi kidney transplantation in pediatric population. Nevertheless, reluctance to pursue an ABOi still remains pervasive. This could be ascribed to various legitimate reasons, namely less extensive pediatric ABOi data, technical difficulties encountered during PP, cost restraints, and concerns regarding higher rates of antibody-mediated rejection, infectious complications, and post-transplant lymphoproliferative disorder as compared to adults. However, given the similar excellent outcomes of both ABOi and ABOc kidney transplantation, clinicians should consider this option sooner if a compatible donor or swap is not available. Here, we describe the outcomes of three pediatric ABOi performed at our institute in India (from 2014 till now), wherein distinct apheresis modalities had been employed in each desensitization protocol, and our techniques evolved with advancing science in apheresis. This case series includes India's first published pediatric ABO-incompatible transplant (Case 2) and the youngest child to undergo ABO-incompatible renal transplant in SAARC nations (Case 3).

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Section: Discussionmentioning

confidence: 85%

Pediatric ABO‐incompatible kidney transplantation: Evolving with the advancing apheresis technology: A single‐center experience

Sethi

Bansal

Wadhwani

et al. 2018

Pediatric Transplantation

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“…21 Incidences of graft rejection might be increased during the past few years because of shifting boundaries for donor acceptance and because increasingly more ABO-incompatible transplants are being performed in our center. 22 A causal association between stent material and rejection episodes seems highly unlikely.…”

Section: Discussionmentioning

confidence: 99%

Untitled

Ooms

Spaans²,

Betjes³

et al. 2017

Exp Clin Transplant

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Objectives: The aim of this study was to evaluate the effects of 2 types of external ureteral stents on the number of urological complications after kidney transplant. Materials and Methods: Data were retrospectively collected from 366 consecutive transplants performed between January 2013 and January 2015 in our hospital, in which an external ureteral stent was placed during surgery and removed after 9 days. Urological complications were defined as urinary leakage or ureteral stenosis requiring percutaneous nephrostomy placement. Results: A total of 197 patients received a straight stent with 2 larger side holes (type A; 8F "Covidien" tube; Covidien, Dublin, Ireland) and 169 patients received a single J stent with 7 smaller side holes (type B; 7F "Teleflex" single J stent; Teleflex Medical, Athlone, Ireland). We found a significantly higher number of percutaneous nephrostomy placements with type A stents, with 34 (17%) versus 16 (9%) in type B (P = .030). Reason for percutaneous nephrostomy placement, occurrence of stent dysfunction, and need for early removal (< 8 days) were equal in both groups (P = .397), whereas incidence of rejection and urinary tract infection were higher in type B stent group. Patient and graft survival did not differ between the groups. Conclusions: Use of the type B stent was associated with less urological complications compared with the type A stent.

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Immune Desensitization Allows Pediatric Blood Group Incompatible Kidney Transplantation

et al. 2017

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Post‐Transplantation Immunoadsorption Can Be Withheld in ABO‐Incompatible Kidney Transplant Recipients

Abstract: After ABO-incompatible kidney transplantation, postoperative plasma exchange (PE) or immunoadsorption (IA) is performed per protocol or depending on postoperative A/B-titers to prevent acute rejection.

Cited by 3 publications

References 28 publications

Pediatric ABO‐incompatible kidney transplantation: Evolving with the advancing apheresis technology: A single‐center experience

Pediatric ABO‐incompatible kidney transplantation: Evolving with the advancing apheresis technology: A single‐center experience

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Immune Desensitization Allows Pediatric Blood Group Incompatible Kidney Transplantation

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