Post-synthetic modification of polyvinyl alcohol with a series of N-alkyl-substituted carbamates towards thermo and CO₂-responsive polymers

Abstract

Intensive efforts have been devoted to the synthesis of thermoresponsive polymers with terminal N-alkyl-substituted groups.

Polyvinyl Alcohol‐Based Thermogel with Tunable Gelation and Self‐Healing Property

“…Simultaneously, the pH of the solution also rapidly decreases (Figure S10, Supporting Information). This clearly is associated with the protonation of terminal amino groups of DEEDA appedants . When CO 2 injection is stopped, the N 2 is used to purge the solution so that the unreacted but dissolved CO 2 is removed.…”

“…In our previous work, a new family of N ‐alkyl substituted carbamate‐modified PVA derivatives, which shows multiple responses to CO 2 , pH, and temperature . The features of responsibility have introduced potential applications of smart actuators .…”

“…Herein, a newly injectable, thermogelated, and self‐healing polymeric platform with simple structure: borax crosslinked N 1 ,N 1 ‐diethylethane‐1,2‐diamine (DEEDA) modified PVA (denoted as PVA‐DEEDA‐Borax hereafter), is present in this work ( Figure a, with synthetic details in the Supporting Information). PVA‐DEEDA is prepared via a straightforward postsynthetic modification, and then borax is added to the PVA‐DEEDA solution with a moderate concentration (<20 mg mL −1 ) to yield the PVA‐DEEDA‐Borax solution at low temperature. This postsynthetic modification and crosslinking is characteristic of adding functional segments on a well‐defined polymer.…”

Thermoresponsive Polymers Based on Tertiary Amine Moieties

“…In recent years, thermoresponsive polymers based on tertiary amine moieties, e.g., tertiary amine functionalized poly((meth)acrylamide)s, [ 74–85 ] poly((meth)acrylate)s, [ 86–99 ] poly(styrene)s, [ 100,101 ] poly(vinyl alcohol)s, [ 102,103 ] and poly(ethylene oxide)s, [ 104,105 ] have aroused considerable interest and become an important family of thermoresponsive polymers, which exhibit LCST and/or UCST in water or aliphatic alcohols. Poly(2‐(dimethylamino)ethyl methacrylate) (PDMAEMA), [ 86,87,94–98 ] which exhibits tunable LCST at the temperature ranging from 40 to 55 °C, may be the most popular one.…”

Synthesis, characterization, and drug release activity of structurally modified poly(vinyl alcohol)

“…The structure of PVA was modified with 4‐maleiidohenylisocyanate and its thermal and mechanical properties were tested . Similarly, the structure of PVA was modified with chitosan, rifambin, glycidylmethacrylate, glycoside, N ‐alkyl‐substituted carbamates, 3‐diethylaminopropylamine, succinimide, propargylamine, poly(ɛ‐caprolactone), diethylchlorophosphate, soy bean oil triglycerides, and natural rubber latex for various end user applications. In 2010, Wang and Hsieh modified the structure of PVA with PEG diacrylchloride.…”