2007
DOI: 10.1111/j.1440-1754.2007.01109.x
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Post‐streptococcal glomerulonephritis in Sydney: A 16‐year retrospective review

Abstract: Significant differences are seen in a low-incidence urban Australian population with PSGN when compared with endemic or epidemic disease in high-risk populations. The higher rates of complications that were seen compared with previously studied populations need further clarification.

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Cited by 47 publications
(35 citation statements)
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“…Even though it is not rare not to find any previous infection to explain the APSGN [24,25], in our study 26% (13/50) of the children had no skin or respiratory infection before the illness. The same proportions were observed by Blyth et al in an Australian cohort [26].…”
Section: Discussionsupporting
confidence: 88%
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“…Even though it is not rare not to find any previous infection to explain the APSGN [24,25], in our study 26% (13/50) of the children had no skin or respiratory infection before the illness. The same proportions were observed by Blyth et al in an Australian cohort [26].…”
Section: Discussionsupporting
confidence: 88%
“…In five children (10%), the only sign was microscopic haematuria, and five other children were asymptomatic. More severe clinical presentations (congestive cardiac failure, severe arterial hypertension, and/or encephalopathy) were observed in the same proportions as in other endemic areas [14,26]. The level of the C3 fraction of complement was lower in these severe clinical presentations (0.2±0.1 vs. 0.4±0.4 g/l in non-severe forms, p=0.02), but not in patients with initial renal failure (Table 3).…”
Section: Discussionsupporting
confidence: 55%
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“…8 In contrast, in tropical northern Australia APSGN is far more common and outbreaks have previously been reported in Aboriginal communities. 9,10 In the Northern Territory (NT), which comprises a semi-arid central Australian region and a tropical northern region, sporadic cases occur each year but also larger outbreaks in the northern region are documented by public health authorities around every 5-7 years.…”
Section: Introductionmentioning
confidence: 97%
“…It results from an antecedent infection of the skin (pyoderma) or throat (pharyngitis, tonsillitis) caused by nephritogenic strains of group A betahemolytic streptococci and follows throat infection with group A streptococci M protein types 1, 2, 3, 4, 12, 25, and 49 and pyoderma with streptococci M types 2, 47, 49, 55, 57, and 60 [1][2][3][4]. The overall risk of developing PSAGN after infection by these nephritogenic strains is about 15%.…”
Section: Introductionmentioning
confidence: 99%