Post-poliomyelitis syndrome

Abstract

Post-poliomyelitis syndrome (PPS) is a common neurological disorder that occurs in a large proportion of individuals who have recovered from paralytic poliomyelitis. The main clinical features are new weakness, muscular fatigability, general fatigue, and pain. The primary criteria necessary for the diagnosis of PPS are a history of paralytic poliomyelitis, partial or complete recovery of neurological function followed by a period of stability (usually several decades), persistent new muscle weakness or abnormal muscle fatigability, and the exclusion of other causes of new symptoms. The cause of PPS remains unclear, but is likely due to a distal degeneration of enlarged post-poliomyelitis motor units. Contributing factors to PPS may be aging (with motor neuron loss), overuse, and disuse. PPS is usually a slowly progressive neuromuscular disease. Although there is no specific treatment for PPS, an interdisciplinary management program can be useful in controlling symptoms.

West Nile Virus–associated Flaccid Paralysis Outcome

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Physical activity in persons with late effects of polio: A descriptive study

“…It is one of the most common neurological conditions and it Physical activity in late effects of polio 6 is estimated that over 10 million people worldwide will need health care and rehabilitation over the next decades as a result of their acute poliomyelitis infection (14). Late effects of polio are characterized by new symptoms or impairments, such as muscle weakness, muscle fatigue, general fatigue, cold intolerance, and musculoskeletal pain both at rest and during PA (14)(15)(16)(17).…”

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