Safety culture encompasses the knowledge, procedures and practices that are shared by the actors of an organization regarding the control of risks related to its activities. In the hospital environment, the introduction of a safety culture in the care services is still not very evident. Generally, it is focused on the patient, even though health professionals are also constantly exposed to various risks. Indeed, the infectious risk secondary to blood exposure accidents constitutes a serious threat to the health of healthcare professionals. This requires improvements in the knowledge and attitudes of the safety culture by all operational and management staff in hospitals. The aim of this work is to study the knowledge and attitudes of health professionals regarding the safety culture towards blood exposure accidents, using a questionnaire that will allow to evaluate the perception of safety in a Moroccan hospital.