Post-operative Stereotactic Radiosurgery of Malignant Melanotic Schwannoma

Hall, Jennifer C; Chang, Steven D.; Wilson, Thomas J.; Ganjoo, Kristen N.; Toland, Angus; Vogel, Hannes; Pollom, Erqi L.; Rahimy, Elham

doi:10.7759/cureus.22849

Cited by 4 publications

(2 citation statements)

References 16 publications

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“…Patients should be followed up for a long time postoperatively, including screening for Carney syndrome, especially in younger patients [ 3 ]. The efficacy of chemoradiotherapy for this disease is uncertain, but there is some literature suggesting that stereotactic radiotherapy can be used to treat this disease, but more evidence-based evidence is lacking [ 8 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

Malignant melanotic schwannoma of the cervical spinal cord: a case report

Chen,

Wei

2024

BMC Neurol

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Spinal cord malignant melanotic schwannoma (MMNST) is a rare central nervous system tumor that originates from the spinal cord or spinal myelin sheath cells and can produce melanin. This type of tumor is usually highly aggressive and malignant, with a poor prognosis. The clinical manifestations of spinal cord MMNST are mainly pain, paresthesia, muscle weakness, muscle atrophy, etc., and symptoms of spinal cord compression, such as intestinal and bladder dysfunction, paraplegia, etc. Early detection of tumor lesions can facilitate tumor removal, improve patients’ quality of life, and prolong patients’ survival. In this case report, a 27-year-old young woman was diagnosed with MMNST of the cervical spinal cord due to weakness of her limbs in our hospital, and underwent surgical resection. The patient’s limbs returned to normal after surgery. It is worth mentioning that the patient visited our hospital 7 months ago for “right upper limb pain for 3 days” and was diagnosed with a cervical spine space-occupying lesion at the same position this time, but the pathology report was “hemosiderosis”. The patient’s limbs returned to normal after surgery. It is worth mentioning that the patient visited our hospital 7 months ago for “right upper limb pain for 3 days” and was diagnosed with a cervical spine space-occupying lesion at the same position this time, but the pathology report was “hemosiderosis”. This case report aims to raise awareness of the problem of spinal cord MMNST and contribute to greater knowledge of this rare tumor. This case report aims to raise awareness of the problem of spinal cord MMNST and contribute to greater knowledge of this rare tumor.

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Section: Discussionmentioning

confidence: 99%

Malignant melanotic schwannoma of the cervical spinal cord: a case report

Chen,

Wei

2024

BMC Neurol

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“…At the time of diagnosis, 16% of patients had metastatic disease, with the lungs as the predominant site of metastasis [13]. Malignant schwannoma has a high risk of local recurrence and a propensity to arise in areas already subjected to radiation [14].…”

Section: Discussionmentioning

confidence: 99%

Uterine schwannoma during pregnancy: a rare case report

Spina,

Cignini,

Bisogni

et al. 2024

Ital J Gynaecol Obstet

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Background. Schwannomas are nerve sheath neoplasms that form from Schwann cells. These tumors are normally found as a solitary, painless, slow-growing mass of varied size, and they are usually asymptomatic. The uterine cervix is an exceptionally unusual place of occurrence in the female genital system, and schwannomas are infrequent in this area. The purpose of this case report was to contribute to the growing body of knowledge regarding a rare site of schwannomas incidence and its subsequent implications during a normal and physiologic pregnancy.Case presentation. A 37-year-old lady 0 para came to us in May 2011 at 6 weeks pregnant for obstetric care for her first pregnancy. With the exception of vitamins throughout pregnancy, the lady had no visible ailments and did not take any medicine. The patient underwent C-section at 39 weeks gestation in December 2011 for cephalo-pelvic disproportion. A grayish oval solid lesion 3 × 2 × 1 cm in diameter was removed from the uterine cavity and sent for pathological examination immediately after the placenta was expelled. Histopathology and immunohistochemistry reveled a benign schwannoma. There were no effects noted for the present pregnancy or the following one. Conclusions.According to the current literature, diagnosis of this tumor during pregnancy and its eventual impact on pregnancy requires more research and inquiry. The goal of this case study was to add to the current scientific knowledge concerning the prevalence of schwannomas and their consequences during a normal and healthy pregnancy.

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