Post-operative Rehabilitation of Atypical Femoral Fracture in a Single Center

Abstract

Increasing numbers of reports have described atypical femoral fracture (AFF) in patients being treated with oral bone resorption inhibitors, such as bisphosphonates. Most AFF patients undergo surgical treatment. However, there is little information about post-operative rehabilitation and patient activity levels after surgery for such fractures. Here we report the outcome of surgical treatment and postoperative rehabilitation for AFF at a single center in Japan. Methods: We retrospectively reviewed 13 patients (14 AFFs) who underwent surgery at Nagano Matsushiro General Hospital between January 2013 and December 2016. The clinical backgrounds of the patients were evaluated. Results: The patients comprised 1 man (1 AFF) and 12 women (13 AFFs). The mean age at surgery was 77.7±7.1 years (mean±SD). Before AFF occurred, 12 of the 13 patients had used bisphosphonates for osteoporosis. An intramedullary nail was inserted in all patients. Partial weight bearing was started on average 2 weeks after surgery, and full weight-bearing gait was permitted on average 3 weeks after surgery. The average time to bone union was 9.9±6.1 months, ranging from 3 to 23 months. None of the patients required additional surgical procedures, including revision surgery for pseudoarthrosis (nonunion) or delayed union. Before AFF, 12 patients walked independently, and 1 patient walked with a single cane. At the final follow-up (mean duration: 34.5±15.7 months), 8 patients could walk independently and 5 patients walked with a single cane. Conclusions: We recognized that rigid fixation for AFF supported early weight-bearing gait after surgery.

Does the Nonunion Rate of Atypical Femoral Fractures Differ According to Fracture Site?: A Meta-Analysis

“…1 ). Among 29 studies, 11 cohort articles included both sites of AFF (subtrochanteric and midshaft), 7 13 16 17 18 19 20 21 22 23 24) 9 cohort studies reported outcomes after surgery of subtrochanteric AFFs, 6 9 10 11 14 25 26 27 28) and 9 single cohort studies reported midshaft AFF. 8 12 15 29 30 31 32 33) The overall incidence of nonunion was 10.3% (77 / 742) in total, 17.5% (52 / 297) in the subtrochanteric AFFs group, and 5.6% (25 / 445) in the midshaft AFFs group ( Table 1 ).…”