Post-operative pain relief in children following extraction of carious deciduous teeth under general anaesthesia: a comparison of nalbuphine and diclofenac

Abstract

In a randomized double-blind study 60 children, undergoing the extraction of carious deciduous teeth under day-case general anaesthesia, were assigned to receive either intravenous nalbuphine hydrochloride 0.3 mg kg-1 (n = 21), one or more diclofenac suppositories 12.5 mg to a dose of 1-2 mg kg-1 (n = 19), or no analgesia (n = 20). The duration of anaesthesia was longer in the diclofenac group (9.6 min, SD 3.5) compared with control (7.2 min, SD 2.6) and nalbuphine (6.9 min, SD 3.0) groups respectively (P < 0.05). There were no statistically significant differences in post-operative pain scores during the 45 min post-operative period studied between the three groups using an objective pain score. We conclude that using this methodology we were unable to demonstrate any statistically significant differences between the analgesic effects of either intravenous (i.v.) nalbuphine or diclofenac suppositories compared with control.

Pain relief for paediatric dental chair anaesthesia: current practice in a community dental clinic

“…The use of topical bupivacaine [1] has been described, as well as the use of intravenous agents, for example ketorolac and fentanyl [2]. Diclonefac suppositories have also been used [3]. Infiltration of local anaesthetics is commonly used for oral surgery [4], but is not an established procedure in the community dental setting for simple procedures.…”

Citation analysis as a literature search method for systematic reviews

“…(), the method retrieved Roten, Baker, and Gray (); and in the case of Parekh et al. (), the method retrieved Littlejohn, Tarling, Flynn, Ordman, and Aiken (). Although these publications may have been retrieved and subsequently excluded by the authors of these reviews, it is also possible that they were not retrieved at all.…”

Postoperative pain

“…Comparisons of opioid and NSAID for extractions have shown no difference in analgesia (63,64) but opioids may produce increased PONV (64).…”