Percutaneous transluminal angioplasty (PTA) was used successfully to treat coarctation restenosis in seven patients. The patients were 10 months to 17 years old at the time of the angioplasty, and the initial coarctation repair had been performed 10 months to 16½/2 years previously. PTA reduced the systolic pressure gradient across the coarctation from a mean of 58 mm Hg before the procedure to a mean of 13 mm Hg immediately after PTA. Follow-up has been from 1 to 14 months and indicates that the decrease in the systolic pressure gradient is persistent. Circulation 68, No. 5, 1087-1094, 1983 SURGICAL REPAIR of coarctation of the aorta has been performed since 1945. Recent reviews have indicated that there is a high incidence of recurrence of stenosis at the anastomotic site, particularly if the primary repair is performed in infancy. 1-8 If surgical correction is delayed into later childhood, there would be a risk of persistent hypertension, although the risk of recurrent stenosis would be lessened.9' '°T he mechanism of recurrence of stenosis at the coarctation site has been considered to be the result of one or more factors: (1) incomplete relief of the obstruction at the time of the initial repair, (2) incomplete resection of "abnormal" aortic tissue that may have a tendency to proliferate, (2) failure of the anastomotic site to grow, (4) thrombus formation on the suture line, and (5)
MethodsClinical material. Seven patients underwent percutaneous transluminal balloon angioplasty for treatment of recurrent stenosis in the aorta at the site of previous coarctation repair. The presenting data for these seven patients before the balloon angioplasty are summarized in table 1. The seven patients were divided into four categories based on the type of primary repair performed.Coarctation restenosis (end-to-end anastomosis, three patients) Patient 1. An 1 1-year-old girl had been in congestive heart failure in infancy. When she was 6 months old, a cardiac catheterization revealed severe coarctation of the aorta with a patent ductus arteriosus (PDA). Intra-aortic pressures indicated a 50 mm Hg pressure gradient across the coarctation. At 9 months of age she had surgical resection of the coarctation with an end-toend anastomosis. Subsequently she was asymptomatic, and when followed up in the outpatient clinic she had normal arm blood pressures and a 20 mm Hg lower pressure in her legs. At 11 years old, she had evidence of upper-extremity hypertension with diminished femoral pulses.Patient 2. An 8-year-old boy had been in congestive heart failure in the neonatal period. When he was 11 days old, cardiac catheterization revealed severe coarctation of the aorta and PDA. When he was 12 days old the coarctation was resected and an end-to-end anastomosis was performed. After the surgical procedure he had persistent upper-extremity hypertension with decreased femoral pulses. When he was 8 years old, cardiac catheterization revealed a discrete recurrent coarctation of the aorta.Patient 3. An 8-year-old boy had congest...