Post-mortem magnetic resonance (PMMR) imaging of the brain in fetuses and children with histopathological correlation

Shelmerdine, Susan C.; Hutchinson, J. Ciaran; Sebire, Neil J.; Jacques, Thomas S.; Arthurs, Owen J.

doi:10.1016/j.crad.2017.07.015

Cited by 12 publications

(12 citation statements)

References 72 publications

(58 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Venous stasis is a normal finding following death, but can also equally be misinterpreted as ante-mortem venous thrombosis [31] on SWI images (Fig. 5).…”

Section: Normal Post-mortem Findings/pshysiological Changesmentioning

confidence: 99%

See 1 more Smart Citation

Perinatal post-mortem magnetic resonance imaging (MRI) of the central nervous system (CNS): a pictorial review

et al. 2021

View full text Add to dashboard Cite

Central nervous system (CNS) abnormalities cause approximately 32–37.7% of terminations of pregnancy (TOP). Autopsy is currently the gold standard for assessing dead foetuses and stillborn. However, it has limitations and is sometimes subject to parental rejection. Recent studies have described post-mortem foetal magnetic resonance imaging (MRI) as an alternative and even complementary to autopsy for CNS assessment. Radiologists now play a key role in the evaluation of perinatal deaths. Assessment of foetal CNS abnormalities is difficult, and interpretation of foetal studies requires familiarisation with normal and abnormal findings in post-mortem MRI studies as well as the strengths and limitations of the imaging studies. The purpose of this pictorial review is to report our experience in the post-mortem MRI evaluation of the CNS system, including a description of the protocol used, normal CNS findings related to post-mortem status, abnormal CNS findings in our sample, and the correlation of these findings with histopathological results.

show abstract

“…Venous stasis is a normal finding following death, but can also equally be misinterpreted as ante-mortem venous thrombosis [31] on SWI images (Fig. 5).…”

Section: Normal Post-mortem Findings/pshysiological Changesmentioning

confidence: 99%

“…DWI sequences and the apparent diffusion coefficient (ADC) can also be altered by multiple causes, with maceration being the most common [ 21 ]. Venous stasis is a normal finding following death, but can also equally be misinterpreted as ante-mortem venous thrombosis [ 31 ] on SWI images (Fig. 5 ).…”

Section: Introductionmentioning

confidence: 99%

Perinatal post-mortem magnetic resonance imaging (MRI) of the central nervous system (CNS): a pictorial review

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Assessment should be directed at excluding neural tube defects [27] or caudal regression syndrome, identifying vertebral segmental anomalies and spinal dysraphism. Where these are suspected, further characterisation with skeletal radiographs (i.e.…”

Section: Imaging and Reporting Algorithmmentioning

confidence: 99%

Perinatal post mortem ultrasound (PMUS): a practical approach

2019

View full text Add to dashboard Cite

Declining rates of consent for standard perinatal autopsy has led to a rise in interest for postmortem imaging as an alternative, non-invasive method for investigation of childhood and perinatal deaths. Whilst much interest has focussed on cross-sectional techniques such as postmortem CT (PMCT) or MRI (PMMR), other modalities including postmortem ultrasound (PMUS) have been shown to have reasonable diagnostic accuracy rates, with the added benefit of being more readily accessible and affordable. There is little published information or formal guidance available on preparation for postmortem perinatal ultrasound, views to be obtained and differentiating normal postmortem change from potential abnormalities.This article will focus on the role of perinatal postmortem ultrasound as an alternative imaging method for non-invasive autopsy, with emphasis on imaging technique, practical considerations and commonly encountered case examples.Electronic supplementary materialThe online version of this article (10.1186/s13244-019-0723-9) contains supplementary material, which is available to authorized users.

show abstract

“…Post-mortem experiment: post-mortem foetus Post-mortem MRI (PM-MRI) as part of minimally invasive autopsy is an increasingly important clinical application of MRI (Arthurs et al, 2015a;Arthurs et al, 2015b;Griffiths et al, 2005;Norman et al, 2016;Papadopoulou et al, 2016;Shelmerdine et al, 2017) where quantitative mapping could be useful e.g. in the determination of autolysis.…”

Section: In Vivo Experiment: Focal Epilepsy and Porencephalic Ventricmentioning

confidence: 99%

Flexible proton density (PD) mapping using multi-contrast variable flip angle (VFA) data

et al. 2019

View full text Add to dashboard Cite

show abstract

Post-mortem magnetic resonance (PMMR) imaging of the brain in fetuses and children with histopathological correlation

Cited by 12 publications

References 72 publications

Perinatal post-mortem magnetic resonance imaging (MRI) of the central nervous system (CNS): a pictorial review

Perinatal post-mortem magnetic resonance imaging (MRI) of the central nervous system (CNS): a pictorial review

Perinatal post mortem ultrasound (PMUS): a practical approach

Flexible proton density (PD) mapping using multi-contrast variable flip angle (VFA) data

Contact Info

Product

Resources

About