Post-mortem estimation of gestational age and maturation of new-borns by CT examination of clavicle length, femoral length and femoral bone nuclei

Feld, Katharina; Bonni, M.; Körber, Friederike; Eifinger, Frank; Banaschak, S.

doi:10.1016/j.forsciint.2020.110391

Cited by 3 publications

(2 citation statements)

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“…Three subgroups (a) 25À27 weeks' gestational age, (b) 28 À36 weeks' gestational age and c) 37À43 weeks' gestational age were established. The age of gestation of the cadavers was compared to the documented gestational age by measuring the length of the clavicle according to Sherer et al 14 and Feld et al 15 Spectral-CT examination (iQon 1 , Dual-layer Spectral-CT, Phi-lipsTM, The Netherlands) were performed, raw data were reconstructed using a soft kernel (soft tissue window) and an ultra-hard kernel (bone window), saved in DICOM format and analysed on a clinical PACS workstation (IMPAX-EE 1 V.R20XVISU2, AGFA, Germany). CT-scans were analysed.…”

Section: Methodsmentioning

confidence: 99%

Finding alternative sites for intraosseous infusions in newborns

et al. 2021

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Aim: Intraosseous (IO)-access plays an alternative route during resuscitation. Our study in preterm and term stillborns was performed to find alternative IO puncture sites beside the recommended proximal tibia. Methods:The cadavers used were legal donations. 20 stillborns (mean: 29.2weeks, IQR 27.1À39.6) were investigated. Spectral-CT were analysed to calculate the diameter and circumferences of: i) proximal humerus ii) distal femur iii) proximal tibia iv) diaphyseal tibial. Contrast medium was applied under video documentation to investigate the drainage into the vascular system.Results: In term newborns, diameter of the cortex of the proximal humeral head is 12.1 AE 1.8 mm, distal end of the femur 11.9 AE 3.4 mm and the proximal tibial bone 12.0 AE 2.4 mm with cross-sectional diameter of 113.5 AE 19.7 mm 2 , 120.6 AE 28.2 mm 2 and 111.6 AE 29.5 mm 2 , respectively. Regarding the preterm groups, there is a strong age-related growth in diameter and cross -sectional size. The diaphyseal area is the smallest in all measured bones with an age-dependent increase and is about half of that of metaphyseal diameters (proximal and distal) and about one third of that of metaphyseal cross sectional areas. The proximal femoral head region has the largest diameter of all measured bones with an egg-shaped formation with an extensive joint capsula. All investigated metaphyseal areas lack a clearly enclosed bone marrow cavity. Infusion of contrast medium into the distal femoral end and the proximal humerus head demonstrate the drainage of contrast medium into the central venous system within seconds. Conclusion:Proximal humeral head and distal femoral end might be alternative IO areas which may lead to further IO puncture sites in neonates.

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Section: Methodsmentioning

confidence: 99%

Finding alternative sites for intraosseous infusions in newborns

et al. 2021

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“…The critical obstetrical dimension is fetal shoulder width, which varies to some extent with shoulder position, but is constrained by clavicular length. While clavicular growth from prenatal to postnatal stages has been studied in humans mainly as a measure to estimate the age at death ( 44 – 48 ), the obstetrical relevance of clavicular growth trajectories remains unknown. Specifically, we hypothesize that, in humans, the prenatal development of the shoulders is obstetrically constrained.…”

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Human shoulder development is adapted to obstetrical constraints

Kawada

Nakatsukasa

Nishimura

et al. 2022

Proc. Natl. Acad. Sci. U.S.A.

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Significance During human birth, the risk of complications is relatively high because of the comparatively large dimensions of the fetal head and shoulders relative to the maternal birth canal. Here we show that humans exhibit a developmental mode of the shoulders that likely contributes to mitigating obstetrical problems. Human shoulder growth is decelerated before birth but accelerated after birth, which stands in contrast to the more uniform shoulder growth trajectories of chimpanzees and macaques. This indicates that fetal developmental modifications were required during human evolution not only in the head but also in the shoulders to compensate obstetrical constraints.

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Bibliometric Analysis on the Trend of the Computed Tomography (CT)-Related Studies in the Field of Forensic Science

2020

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The computed tomography (CT) technique has attracted much attention as a promising tool for non-invasive diagnosis and examination in the field of forensic science. The purpose of this study is to assess the trend in CT-related forensic studies through bibliometric methods and thus present a holistic idea about the application of CT in the field of forensic science of the past and present. A total of 2084 articles published in the Scopus index journals between 1978 and 2020 were analyzed using VOSviewer 1.6.15. A drastic increase in the number of CT-related articles was noticed in forensic science since the early 2000s. Switzerland, having the most productive institution (University of Zurich) and author (Michael J. Thali), contributed most to the increasing number of publications. Forensic Science International was the top journal, where approximately 12.5% of the articles (261 out of 2084) have been published. CT was frequently used for autopsy and diagnosis purposes, but recently its applicability has expanded to the field of forensic anthropology and personal identification. This research is expected to provide researchers using CT with not only an understanding about past research trends but also an insight about future research topics and potential collaborative opportunities.

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Post-mortem estimation of gestational age and maturation of new-borns by CT examination of clavicle length, femoral length and femoral bone nuclei

Cited by 3 publications

References 17 publications

Finding alternative sites for intraosseous infusions in newborns

Finding alternative sites for intraosseous infusions in newborns

Human shoulder development is adapted to obstetrical constraints

Bibliometric Analysis on the Trend of the Computed Tomography (CT)-Related Studies in the Field of Forensic Science

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