Post-lockdown respiratory virus epidemiology: a monocentric observational study

Presti, S.; Bianco, M. Lo; Mollica, F.; Papale, M.; Parisi, G.F.; Leonardi, S.

doi:10.56164/pediatrrespirj.2022.03

Cited by 2 publications

(5 citation statements)

References 17 publications

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“…In a previous study, we documented the initial outbreak of respiratory viruses within a pediatric cohort consisting of 62 bronchiolitis patients, following the relaxation of nonpharmaceutical interventions (NPIs) designed to contain COVID‐19. Our study revealed emerging epidemiological trends during the 2021–2022 season 7 . The study continued into the following year as well and revealed that the prevalence of respiratory viruses, such as RSV, MPV, influenza A/B, and RV, increased after the relaxation of NPIs and in the second season compared to the first, there was a higher prevalence of these viruses 8 .…”

Section: Introductionmentioning

confidence: 51%

Section: Discussionmentioning

confidence: 94%

“…Our study revealed emerging epidemiological trends during the 2021-2022 season. 7 The study continued into the following year as well and revealed that the prevalence of respiratory viruses, such as RSV, MPV, influenza A/B, and RV, increased after the relaxation of NPIs and in the second season compared to the first, there was a higher prevalence of these viruses. 8 To monitor the epidemiological changes triggered by the pandemic, a new surveillance study until the last respiratory virus epidemic season has been conducted.…”

Section: Introductionmentioning

confidence: 98%

“…This finding further reinforces the notion that the severity of bronchiolitis caused by viruses other than RSV increased significantly, during the last epidemic. Bronchiolitis caused by viruses other than RSV appeared to be more severe in the 2022-2023 season compared to bronchiolitis caused by non-RSV viruses in the 2021-2022 season 7. The severity of bronchiolitis has also been evaluated considering the CRS score: during the 2022-2023 epidemic season, there was no significant difference in severity, as assessed by the CRS score, between RSV and non-RSV bronchiolitis (p > .05).…”

mentioning

confidence: 99%

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Epidemiological shifts in bronchiolitis patterns and impact of the COVID‐19: A two‐season comparative study

Presti,

Manti,

Gammeri

et al. 2024

Pediatric Pulmonology

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BackgroundBronchiolitis is a common lower respiratory tract infection (LRTI) affecting infants and young children. Respiratory syncytial virus (RSV) has historically been the primary causative agent, but other viruses also contribute to the LRTI epidemiology. Recent changes in epidemiology and clinical patterns due to the coronavirus disease 2019 (COVID‐19) pandemic have raised concerns. This study aims to analyze the impact of the pandemic on bronchiolitis epidemiology and severity.MethodsTwo consecutive bronchiolitis seasons (October 2021 to March 2022 and October 2022 to March 2023) were compared. Data on viral agents, hospitalization duration, clinical severity, and respiratory support requirements were collected from pediatric patients at San Marco Hospital, University of Catania.ResultsIn the 2021–2022 season, RSV was the predominant virus (40%), followed by other viruses, with mild clinical outcomes. In the 2022–2023 season, RSV remained prevalent (58.7%), but other viruses, including rhinovirus (RV) and influenza, showed a significant increase (p < .05) in bronchiolitis cases and severity. Notably, RSV‐related bronchiolitis did not exhibit greater severity compared to non‐RSV cases in the 2022–2023 season, contrary to the previous year.ConclusionThe COVID‐19 pandemic appears to have shifted the epidemiological landscape of bronchiolitis, with a peak incidence in November instead of January/February. Non‐RSV viruses (RV, influenza A and B, as well as metapneumovirus) have gained prominence, possibly due to viral competition and reduced pandemic‐related restrictions. Traditionally, RSV has been the primary pathogen responsible for most bronchiolitis cases. Nonetheless, the findings of this study indicate a shifting landscape in bronchiolitis etiology, with RSV gradually diminishing in its role. Contrary to the previous year, RSV‐related bronchiolitis did not exhibit greater severity compared to non‐RSV cases in the 2022–2023 season.

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Section: Introductionmentioning

confidence: 51%

Section: Discussionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 98%

mentioning

confidence: 99%

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Epidemiological shifts in bronchiolitis patterns and impact of the COVID‐19: A two‐season comparative study

Presti,

Manti,

Gammeri

et al. 2024

Pediatric Pulmonology

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“…These reductions in community infection rates have resulted in fewer hospitalizations and deaths associated with non-SARS-CoV-2 respiratory infections [ 18 ]. In a previous study, we described the first epidemic of respiratory viruses in a pediatric cohort of 123 patients after the easing of NPIs for the containment of COVID-19, reporting new epidemiological trends in the 2021–2022 season [ 19 ]. In the first post-pandemic epidemic, a multicenter Italian study demonstrated an early onset of the epidemiological curve for RSV and revealed that SARS-CoV-2 exhibited competitive pressure on other respiratory viruses [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

Comparative Analysis of Pediatric Hospitalizations during Two Consecutive Influenza and Respiratory Virus Seasons Post-Pandemic

Presti,

Manti,

Gambilonghi

et al. 2023

Viruses

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Background: The COVID-19 pandemic has had a significant impact on the epidemiology of respiratory viruses. Non-pharmaceutical interventions (NPIs) led to a dramatic reduction in respiratory infections. However, the long-term effects on respiratory virus epidemiology remain unclear. Materials and Methods: We conducted a comparative study on hospitalized pediatric patients with respiratory illness during two seasons: 1 October 2021 to 15 March 2022 and 1 October 2022 to 15 March 2023. We compared the type of virus, mean duration of hospitalization, and disease severity. Results: In the first season, 47.1% of patients (65/138) tested positive for at least one respiratory virus, with respiratory syncytial virus (RSV) being the most frequent (23.2%). In the second season, 82.9% of patients (102/123) tested positive, with RSV and Rhinovirus being the most prevalent (28.38% and 27.03%, respectively). Other viruses, such as Influenza A/B, Metapneumovirus, and Adenovirus, also showed increased prevalence. Disease severity and mean duration of hospitalization were similar between the two seasons. Conclusions: Our study highlights increased prevalence in respiratory viruses, including RSV and Rhinovirus, following the easing of NPIs. The prevalence in respiratory viruses, including RSV and Rhinovirus, increased in the second season compared to the first one. Interestingly, RSV’s peak incidence shifted from February to November. The emergence of rhinovirus as the most prevalent respiratory virus during certain months suggests viral competition and dynamic changes in viral circulation. The overall severity of respiratory infections remained relatively stable between the seasons.

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Post-lockdown respiratory virus epidemiology: a monocentric observational study

Cited by 2 publications

References 17 publications

Epidemiological shifts in bronchiolitis patterns and impact of the COVID‐19: A two‐season comparative study

Epidemiological shifts in bronchiolitis patterns and impact of the COVID‐19: A two‐season comparative study

Comparative Analysis of Pediatric Hospitalizations during Two Consecutive Influenza and Respiratory Virus Seasons Post-Pandemic

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