Post-laparoscopy predictive factors of achieving pregnancy in patients treated for infertility.

Abstract

IntroductionLaparoscopy is a long-established diagnostic and therapeutic method for treating women suffering from infertility. The application of this method of treatment can help achieve pregnancy only if there is correct classification of patients and evaluation of their partner’s reproductive capacity. The main predictors of achieving pregnancy in a couple treated for infertility are the woman’s age, her ovarian reserve, tubal patency, the presence of endometriosis and quality of sperm parameters.AimTo evaluate the effect of endometriosis, ovarian reserve and selected parameters of semen on the effect of achieving pregnancy in patients undergoing laparoscopy.Material and methodsThe most significant predictor of pregnancy in patients undergoing laparoscopy due to infertility was found to be anti-Mullerian hormone (AMH) level after laparoscopy, and the main parameters of semen partners were density, motility and morphology. The number of achieved pregnancies after the laparoscopic treatment of infertility was lower in patients diagnosed with endometriosis, and depended on the severity of the condition.ResultsAs a result of laparoscopic treatment of endometriosis, we found a decrease in ovarian reserve measured by means of AMH.ConclusionsThe most important predictors of pregnancy in patients who underwent laparoscopy due to infertility are post-laparoscopy AMH levels and the main parameters of the partner’s semen: density, motility and morphology. The number of pregnancies after laparoscopic treatment is lower in patients diagnosed with endometriosis, and depends on the severity of the conditio.

Antimüllerian hormone is reduced in the presence of ovarian endometriomas: a systematic review and meta-analysis

“…A total of 17 studies were therefore included at final analysis, for a total of 968 patients with endometrioma and 1874 patients in the control group (Table 1) (18, 19, 26, 28, 41-53). Twelve studies were prospective studies (18, 19, 28, 42-47, 49, 51, 53) and five were retrospective studies (26,41,48,50,52). Six studies included in the control group only patients with non-endometriosis benign ovarian cysts (19,42,46,(49)(50)(51).…”

Interactions of Cortisol and Prolactin with Other Selected Menstrual Cycle Hormones Affecting the Chances of Conception in Infertile Women

“…The importance of AMH in human reproduction is confirmed by research of Hussain et al, Lehmann et al, Reichmanm et al, and Wdowiak et al, which indicate that the chance for achieving pregnancy grows together with an increase in the level of AMH in the case of treatment by the in vitro fertilization method. The abovementioned studies did not unequivocally show whether FSH or AMH has a greater predictive value in achieving pregnancy [ 10 , 27 , 28 , 29 ]. In this study, women with very high AMH (polycystic ovarian syndrome) and those with lowered levels of this hormone (premature menopause) were excluded.…”

“…Secretion of estradiol is conditioned by an adequate ovarian reserve, which is assessed by means of AMH, FSH, and LH. Many scientific reports have analyzed ovarian reserve in the context of achieving pregnancy during infertility treatment [ 9 , 10 ]. Interactions between E2 and P are dependent on the ovarian reserve, and that, as well as a premature rise of progesterone during ovulation, can affect conception [ 11 ].…”

Chronic Inflammation Impairs Male Fertility—A Case-Control Study in Ulcerative Colitis Patients

“…During a study by Wdowiak, A. et al, based on a logistic regression analysis, it was found that together with an increase in such variables as semen density, percentage of morphologically normal spermatozoa, and progressive motility in ejaculate, and the anti-mullerian hormone (AMH) level in female partners, the chance for achieving pregnancy increased, and these relationships were statistically significant. Regarding the case of a partner’s age, viability, mixed antiglobulin reaction (MAR) test for immunoglobulin (Ig)A and IgG, no relationship was observed with achieving pregnancy [ 41 ]. Summing up, considering the classic assessment of semen parameters, it cannot be unequivocally determined as to what extent a decrease in semen parameters would affect the reproductive ability of males with inflammatory bowel diseases.…”