Post-Ganglionic Horner’s Syndrome: An Unusual Presentation of Non-Hodgkin Lymphoma

Resende, Lucilene Silva Ruiz e; Gaiolla, Rafael Dezen; Niéro-Melo, Lígia; Domingues, Maria Aparecida Custódio; Resende, Luiz Antônio de Lima

doi:10.1159/000335521

Cited by 6 publications

(1 citation statement)

References 8 publications

(20 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A 2017 report by Abascal et al documented the onset of ptosis and miosis in a 19 year old male as the initial manifestation of Hodgkin's lymphoma, although the impact of mediastinal adenopathy on the sympathetic chain was unclear (article in Spanish) (16). A separate report described Horner's syndrome in a 35 year old female with cervical adenopathy causing a third order lesion, as confirmed on phenylephrine testing (17). Peltier reported a case of Horner's syndrome from intramedullary spinal cord lymphoma, representing first order injury (18).…”

Section: Discussionmentioning

confidence: 96%

Horner's Syndrome as Initial Manifestation of Possible Brachial Plexopathy Neurolymphomatosis

et al. 2019

View full text Add to dashboard Cite

Introduction: Horner's syndrome is an established clinical finding unique to neoplastic brachial plexopathy.Background: We present the case of a patient who developed Horner's syndrome as the first manifestation of neurolymphomatosis (NL) of the brachial plexus that did not have the usually associated bulky adenopathy/Pancoast syndrome phenotype.Discussion: We discuss the clinical utility of Horner's syndrome with regards to brachial plexopathy of indeterminate etiology, as well as the utility of other diagnostic modalities in NL.Concluding Remarks: NL, particularly of the brachial plexus, is particularly challenging to diagnose. MRI and CSF studies are often inconclusive. FDG-PET imaging can be difficult to get insurance to approve. The presence of Horner's syndrome in brachial plexopathy of indeterminate etiology, even in the absence of bulky adenopathy, should raise clinical suspicion of NL, possibly prompting such interventions as fascicular nerve biopsy.

show abstract

Section: Discussionmentioning

confidence: 96%