2016
DOI: 10.7860/jcdr/2016/19876.8387
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Post Exposure Prophylaxis for Occupational Exposures to HIV and Hepatitis B: Our Experience of Thirteen Years at a Rural Based Tertiary Care Teaching Hospital of Western India

Abstract: Inspite of high incidences of exposures to HIV or Hepatitis B positive source, good efficacy of PEP was observed with no sero-conversion. PEP for HIV was well tolerated; female HCWs were less tolerant. Study emphasized the need for creating awareness about timely reporting of incidence, achieving maximum vaccination against Hepatitis B for all HCWs and need for anti-HBS antibody titre.

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Cited by 14 publications
(9 citation statements)
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“…Similar to our results, in South-Eastern Nigeria, all the affected HCWs received a Zidovudine-based regimen for PEP (Isah et al, 2016). Another study in western India reported a Zidovudine-based regimen as the most commonly prescribed but less well tolerated compared to a Tenofovir-based regimen (Sheth et al, 2016). The same study also reported the use of two-drug regimens being commoner than three-drug regimens.…”
Section: Discussionsupporting
confidence: 88%
“…Similar to our results, in South-Eastern Nigeria, all the affected HCWs received a Zidovudine-based regimen for PEP (Isah et al, 2016). Another study in western India reported a Zidovudine-based regimen as the most commonly prescribed but less well tolerated compared to a Tenofovir-based regimen (Sheth et al, 2016). The same study also reported the use of two-drug regimens being commoner than three-drug regimens.…”
Section: Discussionsupporting
confidence: 88%
“…In studies carried out in several countries to assess adherence to PEP after occupational exposure, similar results were found, as in a study carried out in Denmark, in which the adherence rate was 65.5%. Moreover, a study in India had a 64.6% adherence rate, and in the United States, 62.5% (20,23,27) .…”
Section: Discussionmentioning
confidence: 99%
“…As precauções padrões possuem um papel fundamental no que se refere à minimização da incidência de exposição ocupacional a material biológico. 16 Dessa forma, os profissionais de Enfermagem precisam estar sensibilizados no que se refere às normas de precaução padrão, bem como serem submetidos a uma educação permanente. 17 A Política Nacional de Saúde do Trabalhador e da Trabalhadora, instituída pela Portaria número 1.823/12 do Ministério da Saúde, tem por finalidade a definição dos princípios, diretrizes e estratégias a serem observados pelas três esferas de gestão do Sistema Único de Saúde (SUS), para o desenvolvimento da atenção integral à saúde do trabalhador, visando à promoção e à proteção da saúde dos trabalhadores e à redução da morbimortalidade decorrente dos modelos de desenvolvimento e dos processos produtivos.…”
Section: Discussionunclassified