Post-COVID-19 syndrome symptoms after mild and moderate SARS-CoV-2 infection

Abstract

BackgroundPost-COVID-19 Syndrome (PCS) is characterized by residual symptoms following the initial recovery from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The prevalence of PCS is known to be the highest among severe and critical forms of the disease. However, the occurrence and risk factors for PCS after mild or moderate SARS-CoV-2 infection has not been extensively investigated.MethodsOnline and offline via both paper or mailed questionnaires distributed among Jordan collected between 1st and 21st August 2021, including a total number of 800 respondents, of whom 495 had previous mild to moderate COVID-19 infection. The Newcastle post-COVID syndrome Follow-up Screening Questionnaire was modified, translated, and used as a standard instrument for data collection regarding psychological, medical, and socio-economic symptoms post-infection. The primary outcome was the prevalence of PCS after mild to moderate COVID-19 in Jordan. Secondary outcome was the identification of PCS risk factors.ResultsThe most common PCS symptom was mood disturbance followed by fatigue, anxiety, and myalgia. Female gender significantly increased the risk for multiple PCS symptoms. Age < 30 years was found to be an independent risk factor for myalgia (p = 0.001).ConclusionPCS is highly prevalent among COVID-19 survivors in Jordan, especially in females and patients with comorbidities. Planning physical and mental rehabilitation services is recommended for those patients with PCS symptoms after mild to moderate COVID-19 infection.

Course of fatigue among patients previously hospitalised due to COVID-19

“…Secondly, the results were based on responses given retrospectively by patients a few months after the initial SARS-CoV-2 infection, which could have resulted in potential bias or underestimation of symptoms. Nevertheless, most patients reported residual fatigue, which aligned with findings from previous studies [73]. Thirdly, the NP-COVID questionnaire was created for the purposes of this study; however, it was validated as described before [24].…”

Síndrome pós-COVID-19 e suas complicações a longo prazo: uma revisão sistemática

“…A presente revisão, por fim, teve 8 artigos incluídos, sendo representados detalhadamente na Tabela 1 e sua seleção na Figura 1. A síndrome pós-COVID-19 é considerada uma condição inflamatória difusa e multissistêmica que pode gerar cefaleia diária persistente; fraqueza; perda de olfato e paladar; dores musculares e nas articulações; fadiga crônica; febre persistente; taquicardia; hipertensão ou hipotensão sem causa determinada; dispneia; declínio cognitivo, como, por exemplo, alterações de memória e fadiga mental; mudança no padrão do sono e disfunção autonômica (AL-HUSINAT et al, 2022;KAYAAS-LAN et al, 2021). A disparidade entre a análise estatística dos três sintomas menos aparentes no início, dispneia (42%), fadiga (37 %) e mialgia (21%), modificaram-se, pois continuaram a se manifestar e tornaram mais prevalente, dispneia (32%), fadiga (21%) e mialgia (36%) (MAHMUD et al 2021;DENNIS et al, 2021;MENGES et al, 2021).…”

Long COVID: a review and proposed visualization of the complexity of long COVID

“…A study conducted in Jordan involving 495 non-hospitalised study participants between the ages of 14 and 70 revealed that female participants reported more LC symptoms than male participants. These included fatigue (61 vs 47%), anxiety (51 vs 40%), palpitations (40 vs 30%), weakness (36 vs 24%), breathlessness (33 vs 17%), and change in smell sensation (50 vs 30%) ( 43 ). In another meta-analysis of 20 studies by Maglietta et al.…”