Post Coiling Syndrome Might Predict Recurrence after Coil Embolization of Unruptured Cerebral Aneurysms

Abstract

Recurrence after coil embolization of unruptured cerebral aneurysm is observed at a certain frequency. Factors of the aneurysm itself (maximum diameter, volume, neck length), treatment-related factors (total coil length, coil packing rate), and smoking have been suggested as risk factors of recurrence, but all remain controversial. In this study, we examined the relationship between post coiling syndrome (PCS), which we reported previously, and recurrence after embolization. Methods: The presence or absence of recurrence was retrospectively evaluated as of July 2015 in 36 consecutive patients who underwent coil embolization of unruptured aneurysms at our hospital between June 2008 and April 2010. The patients were followed up by magnetic resonance angiography and plain radiography of the head every 6 months, and the images immediately after the procedure and the latest images were examined using the Raymond classification. Results: After a follow-up period of 53 ± 19 months, no recurrence that led to retreatment was observed, but recurrence was noted in eight patients (22.2%). While there was no significant difference in the frequency of recurrence according to the patients' age, follow-up period, factors of the aneurysm itself (maximum diameter, volume, and neck length), treatment-related factors (total coil length, coil packing rate, percentage of the bioactive coil length relative to the total coil length), or smoking habit, recurrence was observed significantly more frequently in the PCS group. Conclusion: PCS was suggested to be potentially useful as a predictive marker of recurrence.