Post–cesarean section pemphigus vegetans in a young woman treated with methylprednisolone and thalidomide

Qiu, Xuemei; Yuan, Peiyang; Li, Wei; Jiang, Lu

doi:10.1016/j.oooo.2021.02.004

Cited by 4 publications

(2 citation statements)

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“…Balancing the risks of the disease and its complications against potential side effects of medications should be considered to avoid any risk for the mother or child. 5 In our case, the patient had active P Veg and then required treatment throughout her pregnancy. The practice of teledermatology has surged in the last decade.…”

Section: Cerebriform Lesions On the Trunkmentioning

confidence: 66%

“…When it occurs during pregnancy, as in our case, which is exceedingly rare, the management of the disease becomes challenging for clinicians due to the pregnancy and the disease itself. Balancing the risks of the disease and its complications against potential side effects of medications should be considered to avoid any risk for the mother or child 5 . In our case, the patient had active P Veg and then required treatment throughout her pregnancy.…”

Section: Figurementioning

confidence: 85%

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Cerebriform lesions on the trunk

et al. 2021

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Section: Cerebriform Lesions On the Trunkmentioning

confidence: 66%

Section: Figurementioning

confidence: 85%

Cerebriform lesions on the trunk

et al. 2021

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Pyodermatitis-pyostomatitis vegetans: a case report and systematic review focusing on oral involvement

Chrcanovic,

Martins-Chaves,

Pontes

et al. 2024

Oral Maxillofac Surg

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Background Pyodermatitis-pyostomatitis vegetans (PPV) is a rare mucocutaneous disease characterized by multiple pustules and it is considered a marker for inflammatory bowel disease (IBD). The oral manifestations of this condition are referred to as pyostomatitis vegetans (PSV). Purpose To investigate which features could help in establishing the diagnosis of PSV, with or without cutaneous lesions, based on information retrieved from all cases of PSV described in the literature. A case of PV from the authors was also included in the analysis. Methods An electronic search was undertaken, last updated in August 2022. Inclusion criteria included publications reporting cases of PSV, with the diagnosis confirmed by the pathological examination of oral or skin lesions, and presence of IBD. Results/Conclusions Sixty-two publications with 77 cases of PSV and an associated IBD were included. Features that are helpful in establishing the diagnosis of PSV are snail track appearance of oral lesions, an associated IBD (which is not always symptomatic), evidence of intraepithelial clefting on microscopic examination of oral lesions, and peripheral blood eosinophilia. A gold standard for the management of PSV does not exist and high-level evidence is limited. There is no established therapeutic protocol for PSV and management primarily consists of topical and/or systemic corticosteroids, antirheumatic drugs (sulfasalazine, mesalazine), monoclonal antibody (infliximab, adalimumab) immunosuppressives (azathioprine, methotrexate), antibiotics (dapsone), or a combination of these. The risk of recurrence of oral lesions is considerable when the medication dose is decreased or fully interrupted.

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Pregnancy in pemphigus vulgaris: A systematic review

Lan,

Zhang,

Jin

2024

American J Rep Immunol

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ProblemPemphigus vulgaris may worsen during pregnancy, leading to both maternal and fetal complications. The relationship between pemphigus vulgaris and pregnancy remains unclear, and the outcomes and treatments of pemphigus vulgaris during pregnancy have not been extensively discussed.Method of StudyThis article systematically reviews the literature, focusing on the relationship between pemphigus vulgaris and pregnancy. We conducted comprehensive searches in PubMed, Embase, Cochrane Library, and Web of Science databases, identifying 42 studies reporting the disease course, pregnancy outcomes, and management of both pregnancy and pemphigus vulgaris.ResultsA total of 57 cases were included in the analysis, categorized into three distinct forms: pemphigus vulgaris onset before pregnancy (n = 33), onset during pregnancy (n = 20), and onset during the postpartum period (n = 4). Fifty four cases reported treatment strategies, among them, 44 cases (81.5%) initially received systemic corticosteroid therapy during pregnancy. Out of these cases, 7 (15.9%) did not achieve successful remission and required alternative treatment approaches. In terms of pregnancy outcomes, 23 out of 62 neonates (37.1%) exhibited skin lesions or tested positive for anti‐dsg IgG in their serum, while 16 neonates (25.8%) experienced other complications.ConclusionsThese findings highlight the importance of effectively managing pemphigus vulgaris during pregnancy to ensure optimal outcomes.

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Post–cesarean section pemphigus vegetans in a young woman treated with methylprednisolone and thalidomide

Cited by 4 publications

References 66 publications

Cerebriform lesions on the trunk

Cerebriform lesions on the trunk

Pyodermatitis-pyostomatitis vegetans: a case report and systematic review focusing on oral involvement

Pregnancy in pemphigus vulgaris: A systematic review

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