Post-caesarean section analgesia: a comparison of epidural butorphanol and morphine

Palacios, Q.; Jones, Monica M.; Hawkins, Joy L.; Adenwala, J.; Longmire, Stephen; Hess, Kenneth R.; Skjonsby, B. S.; Morrow, Dean H.; Joyce, T. H.

doi:10.1007/bf03009159

Cited by 34 publications

(24 citation statements)

References 20 publications

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“…The finding was similar with the studies done by Abboud et al 10 and Palacios et al 15 . All the patients maintained a respiratory rate greater than 12 throughout the study period in the similar study done by Hunt et al 20 .…”

Section: Discussionsupporting

confidence: 93%

Epidural butorphanol for post operative analgesia in lower limb surgeries: A comparative study with epidural tramadol

Deo

Shrestha

2017

J Chitwan Med Coll

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To compare the efficacy of epidural butorphanol and tramadol for post operative analgesia in lower limb surgeries. Randomized, controlled, double blind, prospective study conducted at Department of Anaesthesia and Critical Care, Chitwan Medical College from September 1st 2015 to August 31st 2016. 60 patients of ASA Grade I and II of either sex, aged between 18-65 years willing for epidural analgesia for post operative analgesia were included in the study. They were divided into two groups: Group B- Butorphanol group and Group T- Tramadol group. Subjects of Group B received 2mg of Butorphanol and 0.25% Bupivacaine making a total volume of 10 ml and that of Group T received 100mg of Tramadol and 0.25% Bupivacaine also making a total volume of 10 ml. Analgesic efficacy was assessed by Visual Analogue Scale (VAS). The onset and duration of analgesia along with side effects were also assessed. The quality of analgesia was studied using time to independent mobilization and overall patient satisfaction. Total number of patients was 60, of ASA Grade I and II, aged between 18-65 years. The mean age of patients in Group B was 42.6±11.7 years and 46.1±11.2 years in Group T. Time of onset of analgesia after epidural injection was 7.4±0.9 minutes in Group B and 12.7±1.5 minutes in Group T and the difference was found to be statistically significant. Duration of analgesia was 317.1±99.1 minutes and 438.8±136.6 minutes in Butorphanol and Tramadol groups respectively which was also statistically significant. Sedation was significantly higher in butorphanol group whereas nausea and vomiting was higher in tramadol group. Quality of analgesia in terms of patient satisfaction was better with epidural butorphanol. Both epidural tramadol and butorphanol were effective in relieving post operative pain however butorphanol had lesser side effects and greater patient satisfaction compared to tramadol but the duration of action was relatively short.

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Section: Discussionsupporting

confidence: 93%

Epidural butorphanol for post operative analgesia in lower limb surgeries: A comparative study with epidural tramadol

Deo

Shrestha

2017

J Chitwan Med Coll

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“…interval and thereafter for every interval, VAS score in group T was always higher than group B throughout till 24 hrs. and the p value of 0.0001 at every interval was statistically highly significant Palacios et al [13] found decreased VAS with epidural Butorphanol, their results are similar to ours study whereas Rawal et al [1] found lower VAS scores with epidural Tramadol 100 mg when compared to our study The probable reason may be that they gave bolus Tramadol by lumbar epidural catheter and infusion of Tramadol by thoracic epidural catheter giving results different than our study.…”

Section: Discussionsupporting

confidence: 79%

A comparison between epidural Butorphanol and Tramadol for postoperative analgesia, sedation and side effects using CSEA technique for surgeries below the level of umbilicus

Wagh

Laheri

2016

Int J of Biomed & Adv Res

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Background and Aims: Epidural analgesia using low doses of local anesthetic agent with or without adjuvants like opioids is a popular, simple, effective and economical way of providing postoperative analgesia. We proposed to evaluate and compare the efficacy of epidural opioids, Butorphanol and Tramadol using Combined Spinal Epidural Analgesia (CSEA) technique for surgeries below the level of umbilicus for postoperative analgesia, sedation and side effects. Methods: In this prospective, double blind, randomized controlled clinical trial, 60 patients aged 18 to 60 years, ASA grade 1 or 2 posted for planned elective surgery below the level of umbilicus were selected. Study Design: The patients were randomly allocated into 2 groups to receive postoperatively either 1 mg of inj. Butorphanol (dissolved in 10 ml of normal saline) (Group B) or 50 mg of inj. Tramadol (dissolved in 10 ml of normal saline) (Group T) epidurally as a bolus dose when the VAS score for pain was more than 4 after the conclusion of surgical procedure as the effect of spinal anaesthesia started wearing off. Statistics and Results:The mean duration of analgesia with tramadol (group T) 6.481 (± 0.86842) hrs. was significantly higher than with butorphanol (group B) i.e., 5.352 (±0.33258) hrs with a p value of 0.0001. Pain scores were also significantly lower statistically in group B as compared to group T. Sedation scores were significantly higher in group B than group T, which was statistically highly significant (p= 0.0001) Conclusion: Both epidural, butorphanol and tramadol provided good postoperative analgesia. The duration of analgesia was longer with tramadol, quality of analgesia was better with butorphanol, sedation more with butorphanol as compared to tramadol and other side effects were comparable

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“…Palacious et al and Ackerman et al reported incidence of pruritus to be 1.4% and 6.7% respectively but none of the patients in our study developed this complication. 7,8 Bharati et al and Parikh et al also did not demonstrate pruritus in any of their patients. 9,10 Respiratory depression was not seen in any patient in the presence cohort.…”

Section: Discussionmentioning

confidence: 71%

A comparative study between epidural butorphanol with bupivacaine and bupivacaine alone for intra-operative and post-operative analgesia in lower limb orthopaedic surgeries

Kar

2016

Int J Res Med Sci

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Post-caesarean section analgesia: a comparison of epidural butorphanol and morphine

Cited by 34 publications

References 20 publications

Epidural butorphanol for post operative analgesia in lower limb surgeries: A comparative study with epidural tramadol

Epidural butorphanol for post operative analgesia in lower limb surgeries: A comparative study with epidural tramadol

A comparison between epidural Butorphanol and Tramadol for postoperative analgesia, sedation and side effects using CSEA technique for surgeries below the level of umbilicus

A comparative study between epidural butorphanol with bupivacaine and bupivacaine alone for intra-operative and post-operative analgesia in lower limb orthopaedic surgeries

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