Post-burn breast reconstruction using an artificial dermis—a long-term follow-up

Abstract

BackgroundFull thickness burns of the chest in childhood are a devastating problem that requires challenging reconstructive options.Integra is a bilaminate artificial dermis composed of shark chondroitin 6-sulfate and bovine collagen. The dermal matrix serves as a scaffold for fibroblasts and endothelial cells. Vascularization of the matrix begins after 2–3 weeks, and eventually, the matrix incorporates with the tissue to create a new dermis. The main advantage of the Integra is that the neodermis is of the same quality as a native dermis.Case presentationIn this case report, we present post-burn breast reconstruction of a 12-year-old girl using Integra, with a long follow-up of 7 years. To the best of our knowledge, there is no published follow-up of breast development after reconstruction with Integra from its beginning point at the age of puberty until after the growing process has terminated.ConclusionsIntegra is a reliable reconstructive tool for burned breast. If done before puberty, it can help in getting normal developing tissue with satisfying esthetic results of size, shape and symmetry.

Dermal regeneration template and vacuum sealing drainage for treatment of traumatic degloving injuries of upper extremity in a single‐stage procedure

“…The mainstream application of these dermis substitutes consists of a two‐stage procedure: placement of the bilayer dermal substitutes and split‐thickness autologous skin grafting after 2–4 weeks. Although favourable functional and aesthetic results of such a procedure were reported, some drawbacks should not be ignored, including immobilization of the upper extremities for 2–4 weeks, need of secondary surgery and increased costs due to prolonged hospital stay …”

“…Although favourable functional and aesthetic results of such a procedure were reported, some drawbacks should not be ignored, including immobilization of the upper extremities for 2-4 weeks, need of secondary surgery and increased costs due to prolonged hospital stay. 18,19 Instead, in this study, we used single-layer Pelnac and defatted avulsed skin in a single-stage procedure to manage the degloving injury of the upper extremities with bone/tendon exposure and found favourable functional and aesthetic results. In the previous report, we used a bilayer Pelnac regeneration template in a singlestage procedure for the successful management of 36 cases of traumatic tissue defects and bone/tendon exposure at the finger tip, without the need of a secondary skin graft, 20 but considering the size, location and severity of the wound, the surgical procedure was not indicated in the cases of the present study.…”

Use of Biologic Agents for Lip and Cheek Reconstruction

“…This is because direct closure is much less expensive when compared with biologic wound agentassisted secondary intention wound healing and does not require multiple weeks of dedicated wound care. 20 Large mucosal defects may be reconstructed with locoregional tissue transfer or by secondary intention wound healing. In regard to locoregional tissue transfer, smaller defects may be reconstructed by advancing the buccal mucosa using a multitude of flap designs to repair the defect.…”

Use of Biologic Agents for Lip and Cheek Reconstruction

“…This is because direct closure is much less expensive when compared with biologic wound agent-assisted secondary intention wound healing and does not require multiple weeks of dedicated wound care. 20 Large mucosal defects may be reconstructed with locoregional tissue transfer or by secondary intention wound healing. In regard to locoregional tissue transfer, smaller defects may be reconstructed by advancing the buccal mucosa using a multitude of flap designs to repair the defect.…”