Post-bariatric Surgery Outcomes and Complications in Patients with Celiac Disease: a Matched Case-Control Study

Hurtado, Maria D.; Cifuentes, Lizeth; Al-Ward, Ruaa; Shah, Meera; Murray, Joseph A.; Mundi, Manpreet S.

doi:10.1007/s11695-021-05601-9

Cited by 4 publications

(10 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The second cohort study was the only study to compare nutritional, clinical, and comorbid outcomes following a variety of bariatric procedures (RYGB, SG, and duodenal switch) in patients with CD compared to those without CD. 14 No statistical significance in nutritional deficiencies were found, and malodourous and oily stools were the only significant GI symptoms experienced more in those with CD. However, the study only included 13 patients with CD and did not specify timing of CD diagnosis.…”

Section: Discussionmentioning

confidence: 90%

“…Full-text review further excluded 7 studies; reasons for exclusion can be found in Figure 1. A total of 9 studies 9-17 were deemed acceptable for the present review, these included: 1 retrospective case series, 1 case series, 5 case reports, and 2 retrospective cohort study (Table 1).…”

Section: Resultsmentioning

confidence: 99%

“…The 9 studies reported a total of 152 patients who underwent bariatric surgery for obesity management and had a diagnosis of CD (Table 1). 9-17 The weighted mean age at time of surgery was 44.2 years (±9.55 years) and 98% of reported patients were female. Reported patient co-morbidities are found in Table 1.…”

Section: Resultsmentioning

confidence: 99%

“…Lastly, Hurtado et al 14 was the only cohort study comparing the effects of bariatric surgery (RYGB, SG, and duodenal switch) in patients with CD against a demographically similar control group who did not have CD. Patients with CD did not experience any statistically different nutritional deficiency and clinical outcomes than those without CD (Table 2).…”

Section: Resultsmentioning

confidence: 99%

“…18 Sharma et al 13 did not meet ideal criteria as the compared groups had differences within their demographics, there was a lack of prospective calculation of study size, and there was no follow-up with patients. Similarly, Hurtado et al 14 also did not meet ideal criteria as study design prevented blinding and study size was not calculated.…”

Section: Resultsmentioning

confidence: 99%

See 4 more Smart Citations

Celiac Disease and Bariatric Surgery: A Systematic Review of Current Literature

Richard

Mocanu

Verhoeff

et al. 2022

Foregut: The Journal of the American Foregut Society

View full text Add to dashboard Cite

Background: Celiac disease (CD) is a clinical entity increasingly recognized in the severe obese population and its impact on outcomes following bariatric surgery is not currently understood. We aimed to systematically review the nutritional and clinical outcomes for patients with obesity and CD following bariatric surgery. Methods: Systematic search of MEDLINE, Embase, Scopus, and Web of Science was conducted in September 2021. Study followed PRISMA guidelines. Studies evaluating adult patients with CD undergoing bariatric surgery were included. Outcomes were descriptive due to limited studies. Results: Our literature review produced 9 studies with 152 patients. The weighted mean age of included patients was 44.2 years (±9.55 years) and 98% (n = 149) were female. Patients diagnosed with CD post-operatively appear to experience substantial perioperative and nutritional complications following bariatric surgery. However, pre-operative diagnosis may allow patient optimization and current studies suggest similar bariatric surgery outcomes can be achieved in these patients when the diagnosis is known. However, this study also highlights a scarcity of evidence evaluating the rate of CD and outcomes for these patients after bariatric surgery. Conclusion: Current literature lacks quality, comparative studies investigating the short- and long-term surgical complications and nutritional outcomes of bariatric surgery within patients who have co-diagnoses of obesity and CD. Despite these limitations, our group recommends pre-operative CD screening in patients experiencing either classical GI symptoms of CD including diarrhea, steatorrhea, bloating, or undifferentiated abdominal pain.

show abstract

Section: Discussionmentioning

confidence: 90%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Celiac Disease and Bariatric Surgery: A Systematic Review of Current Literature

Richard

Mocanu

Verhoeff

et al. 2022

Foregut: The Journal of the American Foregut Society

View full text Add to dashboard Cite

show abstract

Celiac disease and the surgeon

Thompson¹,

Mannon

2022

The American Journal of Surgery

View full text Add to dashboard Cite

Efficacy of Antiobesity Medications in Patients With Celiac Disease on a Gluten-free Diet

Anazco,

Fansa,

Ghusn

et al. 2023

Journal of Clinical Gastroenterology

Self Cite

View full text Add to dashboard Cite

Goals: We aim to describe the weight loss outcomes of patients with celiac disease (CeD) taking antiobesity medications (AOMs) and compare it with the weight loss outcomes of patients without CeD taking AOMs. Background: Increasing rates of obesity and obesity-associated comorbidities have been previously reported in patients with CeD on a gluten-free diet. The effectiveness of AOMs in this population has not been previously described. Methods: In our retrospective cohort study, we matched 39 patients with treated CeD to 78 patients without CeD based on sex and AOM. We assessed the weight loss outcomes at 3, 6, and 12 months after starting the AOM in both cohorts and analyzed if there was a differential response when comparing by type of AOM [injectable glucagon-like peptide 1 (GLP-1) receptor agonists vs. oral non-GLP-1 AOMs]. Results: Both cohorts had similar baseline demographic and anthropometric characteristics. At 12 months, the CeD cohort had a nonsignificantly inferior total body weight loss percentage compared with the cohort without CeD (6.5% vs. 9.5%, P=0.13). The CeD cohort had a similar proportion of patients achieving a total body weight loss percentage of ≥5% than the cohort without CeD (72.7% vs. 72.1%, P=1.00). No significant difference was observed when comparing the weight loss outcomes of injectables (GLP-1 receptor agonists) to oral AOMs. The proportion of patients reporting side effects was similar for both groups, regardless of the type of AOM. Conclusion: Patients with CeD taking AOMs had similar weight loss outcomes to patients without CeD. Hence, AOMs can be a safe and effective therapy for weight management in patients with CeD.

show abstract

Post-bariatric Surgery Outcomes and Complications in Patients with Celiac Disease: a Matched Case-Control Study

Cited by 4 publications

References 34 publications

Celiac Disease and Bariatric Surgery: A Systematic Review of Current Literature

Celiac Disease and Bariatric Surgery: A Systematic Review of Current Literature

Celiac disease and the surgeon

Efficacy of Antiobesity Medications in Patients With Celiac Disease on a Gluten-free Diet

Contact Info

Product

Resources

About