2024
DOI: 10.3390/ijms25169050
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Post-Acute Sequelae and Mitochondrial Aberration in SARS-CoV-2 Infection

Charles Ward,
Beata Schlichtholz

Abstract: This review investigates links between post-acute sequelae of SARS-CoV-2 infection (PASC), post-infection viral persistence, mitochondrial involvement and aberrant innate immune response and cellular metabolism during SARS-CoV-2 infection. Advancement of proteomic and metabolomic studies now allows deeper investigation of alterations to cellular metabolism, autophagic processes and mitochondrial dysfunction caused by SARS-CoV-2 infection, while computational biology and machine learning have advanced methodolo… Show more

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