Possible synthesis of steroid-protein for immunization with a fixed narrow range of the hapten-protein ratio

Uscheva, Anna; Stankov, Bojidar; Zachariev, S.G.; Marinova, C.; Kanchev, L.N.

doi:10.1016/0022-4731(86)90845-9

Cited by 3 publications

(1 citation statement)

References 7 publications

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“…4 In addition, when progesterone-11a-hemisuccinate-BSA was used as conjugate, 36 steroid molecules per protein molecule were found. 5 The conjugates can be prepared by linking the steroid hemisuccinate via an amide bond to the 3-amino groups of lysine in bovine serum albumin (BSA) by means of a mixed anhydride intermediate. 6 Regarding the steroid, in the case of dexamethasone the preparation of 21-hemisuccinate is easy and the product is obtained in high yield.…”

Section: Introductionmentioning

confidence: 99%

An efficient enzymatic preparation of 20-pregnane succinates: chemoenzymatic synthesis of 20β-hemisuccinyloxy-5αH-pregnan-3-one

et al. 2008

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Section: Introductionmentioning

confidence: 99%

An efficient enzymatic preparation of 20-pregnane succinates: chemoenzymatic synthesis of 20β-hemisuccinyloxy-5αH-pregnan-3-one

et al. 2008

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Bovine salivary progesterone: Application to the assessment of ovarian function and early pregnancy diagnosis

Kanchev

Marinova

Stankov

1988

Animal Reproduction Science

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Modeling Multi-typed Structurally Viewed Chemicals with the UMLS Refined Semantic Network

Chen

Morrey

Gu³

et al. 2009

Journal of the American Medical Informatics Association

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The modified RSN provides an enhanced abstract view of the UMLS's chemical content. Its array of conjugate and complex types provides a more accurate model of the variety of combinations involving chemicals viewed structurally. This framework will help streamline the process of type assignments for such chemical concepts and improve user orientation to the richness of the chemical content of the UMLS.

show abstract

Possible synthesis of steroid-protein for immunization with a fixed narrow range of the hapten-protein ratio

Cited by 3 publications

References 7 publications

An efficient enzymatic preparation of 20-pregnane succinates: chemoenzymatic synthesis of 20β-hemisuccinyloxy-5αH-pregnan-3-one

An efficient enzymatic preparation of 20-pregnane succinates: chemoenzymatic synthesis of 20β-hemisuccinyloxy-5αH-pregnan-3-one

Bovine salivary progesterone: Application to the assessment of ovarian function and early pregnancy diagnosis

Modeling Multi-typed Structurally Viewed Chemicals with the UMLS Refined Semantic Network

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