“…This is because CO 2 fixation includes several transient steps which are hard to catch in experiments. They can, however, be assessed in silico, as shown by Fedunov & Sokolov [ 1 ]. Based on density theory and quantum chemical modelling, they confirmed equal probability of the formation of 2,3-enediol and 1,2-enol due to ribulose-1,5-bisphosphate enolisation.…”