Possible role of lncRNAs in amelioration of Parkinson’s disease symptoms by transplantation of dopaminergic cells
A. Amini,
F. Esmaeili,
M. Golpich
Abstract:Long non-coding RNAs (lncRNAs) are biomarkers for diagnosis and treatment of Parkinson’s disease (PD). Since dopaminergic cell transplantation is a clinical method to treat PD, this study investigated the effects of dopaminergic cell therapy on the expression of some lncRNAs and genes related to PD. In this study, Twenty-eight rats were randomly assigned to four experimental groups. The control group (Sal group) received saline injections. The Par group was a PD rat model with 6-hydroxydopamine (6-OHDA) inject… Show more
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