Possible oxidative stress in healthy term newborns

Metsvaht, Tuuli; Ilves, P.; Talvik, T.; Zilmer, K.; Zilmer, M.; Talvik, R.

doi:10.1080/080352599750030509

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Effects Of Probiotic or Synbiotic Supplementation On Total A1

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Cited by 2 publications

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“…Oxidative stress is critical at birth, both for the rapid change from relatively hypoxic intrauterine to the extrauterine environment, where alveolar pO 2 is almost five times higher, as for the mediation of several physiologic processes involved in the finalization of the gestation and delivery (Deligne et al, 1990;Metsvaht et al, 1999;Saugstad, 1990). Cell damage due to oxidative stress during the neonatal period has been associated with disease (Saugstad, 1996) which must be controlled by the antioxidant defense system (Ripalda et al, 1989;Frank et al, 1996).…”

Section: Effects Of Probiotic or Synbiotic Supplementation On Total Amentioning

confidence: 99%

Probiotics and Synbiotics in Lactating Mothers

Nikniaz

Mahdavi

Nikniaz

et al. 2016

Probiotics, Prebiotics, and Synbiotics

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Section: Effects Of Probiotic or Synbiotic Supplementation On Total Amentioning

confidence: 99%

Probiotics and Synbiotics in Lactating Mothers

Nikniaz

Mahdavi

Nikniaz

et al. 2016

Probiotics, Prebiotics, and Synbiotics

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A New Approach to Oxidative Stress and Inflammatory Signaling during Labour in Healthy Mothers and Neonates

Díaz-Castro

Florido

Kajarabille

et al. 2015

Oxidative Medicine and Cellular Longevity

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The objective of the current study was to investigate for the first time and simultaneously the oxidative stress and inflammatory signaling induced during the delivery in healthy mothers and their neonates. 56 mothers with normal gestational course and spontaneous delivery were selected. Blood samples were taken from mother (before and after delivery) both from vein and artery of umbilical cord. Lower antioxidant enzymes activities were observed in neonates compared with their mothers and lower oxidative stress in umbilical cord artery with respect to vein. There was an overexpression of inflammatory cytokines in the mother, such as IL-6 and TNF-α, and, in addition, PGE2 was also increased. Neonates showed lower levels of IL-6 and TNF-α and higher values of sTNF-RII and PGE2 in comparison with their mothers. Parturition increases oxidative damage in the mother, although the indicators of oxidative damage were lower in umbilical cord artery with respect to umbilical vein. The overexpression of inflammatory cytokines reveals that fetus suffers its own inflammatory process during parturition.

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Possible oxidative stress in healthy term newborns

Cited by 2 publications

References 5 publications

Probiotics and Synbiotics in Lactating Mothers

Probiotics and Synbiotics in Lactating Mothers

A New Approach to Oxidative Stress and Inflammatory Signaling during Labour in Healthy Mothers and Neonates

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