“…Research has shown that the PI3K-Akt signalling pathway also plays a significant role in the development and progression of hyperthyroidism. Thyroid hormones can activate this pathway, leading to thyroid hyperfunction, increased cell proliferation, and metabolism [ 41 ]. Furthermore, abnormal activation of the PI3K-Akt pathway is associated with the occurrence and metastasis of tumors related to hyperthyroidism [ 42 ].…”