Possible Effect of Ascorbic Acid against Zinc Oxide Nanoparticles Induced Hepatotoxicity in Swiss Albino Mice
Abstract:Zinc oxide nanoparticles (ZnO-NPs) has long been used in cosmetics and paints without knowing its possible side effects in human beings. This study was conducted to find whether ZnO-NPs toxicity can be reversed by the administration of ascorbic acid in mouse. Swiss albino mice were divided into 4 groups; control group, ascorbic acid (100mg/kg), ZnO-NPs (30mg/kg) and ascorbic acid + ZnO-NPs for 21 alternate days. After that mice were decapitated and liver was preserved for histopathological analysis. Ascorbic a… Show more
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