Possible Early Vertical Transmission of COVID-19 from an Infected Pregnant Female to Her Neonate: A Case Report

Bandyopadhyay, Tapas; Sharma, Abhinav; Kumari, Pratima; Maria, Arti; Choudhary, Rahul

doi:10.1093/tropej/fmaa094

Cited by 15 publications

(14 citation statements)

References 8 publications

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“…IgG antibodies detection remained positive, however IgM antibodies negative. 14 Bandyopadhyay, et al 38 37 2/7 female newborn born to 24-year-old mother who developed with low grade fever. Her RT-PCR pharyngeal swab for SARS-CoV-2 at the time was positive.…”

Section: Single Case Reports Highlighting the Transplacental Vertical Passage Of Sars-cov-2 From Maternal To The Fetal Compartmentmentioning

confidence: 99%

“…( Table 2 ) There were four confirmed cases of transplacental passage of SARS-CoV-2, 26-29 seven cases of probable infection, 30 , 31 , 32 , 33 , 34 , 35 one possible case 36 and two cases of infection proximal to delivery. 37 , 38 …”

Section: Single Case Reports Highlighting the Transplacental Vertical Passage Of Sars-cov-2 From Maternal To The Fetal Compartmentmentioning

confidence: 99%

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Coronavirus Disease 2019 Infection in Newborns

Perlman

Salvatore

2022

Clinics in Perinatology

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Section: Single Case Reports Highlighting the Transplacental Vertical Passage Of Sars-cov-2 From Maternal To The Fetal Compartmentmentioning

confidence: 99%

Section: Single Case Reports Highlighting the Transplacental Vertical Passage Of Sars-cov-2 From Maternal To The Fetal Compartmentmentioning

confidence: 99%

Coronavirus Disease 2019 Infection in Newborns

Perlman

Salvatore

2022

Clinics in Perinatology

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“…The latter newborn however did not convert with IgG reactivity over 21 days. Early infection occurred in a newborn from a vaginal delivery where maternal-newborn contiguity was abrogated [225].…”

Section: Virus Was I D E N T I F I E D B Y I M M U N O H I S T O C H E M I S T R Y I N T H Ementioning

confidence: 99%

A Comprehensive Analysis of Maternal and Newborn Disease and Related Control for COVID-19

Cimolai

2021

SN Compr. Clin. Med.

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The maternal-fetal/newborn unit is established at risk for COVID-19 infection. This narrative review summarizes the contemporary and cumulative publications which detail maternal infection, antenatal and newborn infections, and maternal/fetal/newborn management and prevention. There is a wide spectrum of maternal disease, but the potential for severe disease albeit in a minority is confirmed. COVID-19 carries risk for preterm delivery. Pregnant females can suffer multisystem disease, and co-morbidities play a significant role in risk. Congenital infection has been supported by several anecdotal reports, but strong confirmatory data are few. No typical congenital dysmorphisms are evident. Nevertheless, placental vascular compromise must be considered a risk for the fetus during advanced maternal infections. Clinical manifestations of newborn infection have been mild to moderate and relatively uncommon. Proven antiviral therapy is of yet lacking. The mode of delivery is a medical decision that must include patient risk assessment and patient directives. Both presymptomatic and asymptomatic mothers and offspring can complicate infection control management with the potential for spread to others in several regards. In the interim, infections of the maternal-fetal-newborn unit must be taken seriously both for the disease so caused and the potential for further dissemination of disease.

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“…Though primarily spread through respiratory droplets, researchers have been able to isolate the viral ribonucleic acid in blood, faeces, placental tissue and amniotic fluid raising the possibility of other forms of viral transmission 1 . Data on potential vertical transmission do exist, except it is not specifically proven whether these cases are due to transplacental exposure or due to postnatal contact with COVID-19-positive parents or healthcare workers 2 . We report a case where a newborn displayed probable evidence of vertical transmission of the SARS-CoV-2.…”

Section: Introductionmentioning

confidence: 99%