Possible Anticancer Mechanisms of Some Costus speciosus Active Ingredients Concerning Drug Discovery

El‐Far, Ali H.; Badria, Faried A.; Shaheen, Hazem M.

doi:10.2174/1570163813666160802154403

Cited by 25 publications

(17 citation statements)

References 125 publications

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“…Consequently, several in vivo studies were performed to confirm their beneficial qualities. Medicinal plants are resources of new drugs and many of the modern medicines that improve the health status of animals (El-Far et al, 2016b;El-Far et al, 2017). The active principles of essential oils act as a digestibility enhancer, balancing the gut microbiota and stimulating the secretion of endogenous digestive enzymes and thus improving the growth performance in poultry (Cross et al, 2007;Ayoub et al, 2011;Barakat et al, 2016;El-Far et al, 2016a).…”

Section: Introductionmentioning

confidence: 99%

Effect of Rosemary (Rosmarinus Officinalis) Dietary Supplementation in Broiler Chickens Concerning immunity, Antioxidant Status, and Performance

Ghozlan¹,

El‐Far²,

Sadek³

et al. 2017

AJVS

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Section: Introductionmentioning

confidence: 99%

Effect of Rosemary (Rosmarinus Officinalis) Dietary Supplementation in Broiler Chickens Concerning immunity, Antioxidant Status, and Performance

Ghozlan¹,

El‐Far²,

Sadek³

et al. 2017

AJVS

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“…Medicinal plants are resources of new drugs and many of the modern medicines that improve the health status of animals (El-Far et al, 2016b;El-Far et al, 2017). Thyme (Thymus vulgaris) is a flowering plant in the mint family Lamiaceae.…”

Section: Introductionmentioning

confidence: 99%

Impact of Dietary Thyme (Thymus Vulgaris) on Broiler Chickens Concerning Immunity, Antioxidant Status, and Performance

Abdel-Ghaney¹,

El‐Far²,

Sadek³

et al. 2017

AJVS

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Key words:Broilers, Immunity, Antioxidant, Performance, ThymeThe current study aimed to determine the immune and antioxidant status, and performance of broiler chickens fed diets supplemented with thyme (Thymus vulgaris) leaves powder, as an alternative growth promoter. Therefore, a total of 120 one-day-old Cobb chicks were fed for 35 days with four experimental diets containing thyme powder (0, 5, 10 and 15 g/kg: these were designated groups Control, Thyme I, Thyme II and Thyme III, respectively). The GC-MS analysis of n-hexane extract of thyme showed the presence of isocaryophyllene (33.73%) as a major active ingredient with other antioxidant ingredients. Serum total protein and globulin content was significantly increased in thyme-supplemented chicks at the 3 rd week and significantly increased in Thyme I and III at the 5 th week. Serum albumin and creatinine content and ALT activities were non-significantly increased in the thyme-supplemented chicks at the 3 rd and 5 th weeks. Moreover, serum total cholesterol and triacylglycerol levels were significantly decreased in the thyme groups at the 3 rd and 5 th weeks. Dietary thyme supplementation for broiler was significantly improved serum IgG, IgM, INF-γ, and IL-10 levels, and muscle glutathione content, superoxide dismutase, and glutathione S-transferase with significantly reduced malondialdehyde levels. Regarding to growth performance, thyme 0.5% was non-significantly improved the final body weight, body weight gain, feed conversion ratio, and protein efficiency ratio of broiler chicks. So, these data indicated that incorporation of thyme into the broiler's diet was improved the immune status and antioxidant activities in broilers. Also, production of broilers meat with low levels of lipid peroxidation products. Corresponden ce to: * doaavet792016

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“…The present study has designed as per the field work. [19][20][21]. The antioxidant activity of rhizome extract showed good scavenging activity in methanol and acetone extracts in both DPPH assay & Metal chelating activity.…”

Section: Resultsmentioning

confidence: 99%

Phytochemical Analysis and Antioxidant Potential of Costus speciosus L.

Behera

Devi

Pradhan

et al. 2020

EJMP

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Costus speciosus L. is a tuberous plant commonly available in wetlands and near water bodies throughout Odisha state and used as food and medicinal purposes. The tribal communities of the state used the rhizome to cure joint pain, skin infections and consume as nutraceutical. The above claims are supportive of the fact that the rhizome might have antioxidant potentials and might be rich with diverse secondary metabolites. Keeping this in view an attempt has been made to evaluate the bioactive compounds present in the plant parts and antioxidant potentials in order to validate the tribal claims. Results revealed that the plant parts are rich with phenolic compounds and have antioxidant potential.

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Possible Anticancer Mechanisms of Some Costus speciosus Active Ingredients Concerning Drug Discovery

Cited by 25 publications

References 125 publications

Effect of Rosemary (Rosmarinus Officinalis) Dietary Supplementation in Broiler Chickens Concerning immunity, Antioxidant Status, and Performance

Effect of Rosemary (Rosmarinus Officinalis) Dietary Supplementation in Broiler Chickens Concerning immunity, Antioxidant Status, and Performance

Impact of Dietary Thyme (Thymus Vulgaris) on Broiler Chickens Concerning Immunity, Antioxidant Status, and Performance

Phytochemical Analysis and Antioxidant Potential of Costus speciosus L.

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