Possible adverse drug reaction to parenteral amino acids in an infant: a case report

Abstract

examination revealed wheeze and bilateral crepitations. The vitals recorded on admission were pulse -146 bpm, blood pressure (BP) -88/50 mm of Hg, respiratory rate (RR) -50, temperature -100°C, SpO2 -98% on room air. The blood reports were as mentioned: hemoglobin (Hb) -11.20 g%, total erythrocyte count (TLC) -18,210/mm 3 (N-40, L-53, E-2, M-5, B-0), platelet count -658,290 mm 3 , prothrombin time -18.9, activated partial thromboplastin time -30.4, international normalized ratio -0.7, serum creatinine -0.7, Na + -138.7, K + -5.2. He was started on injection amoxicillin clavulanic acid 150 mg batrachochytrium dendrobatidis (BD) intravenous (IV) along with a salbutamol nebulization.On 04 December, 2013, on the basis of X-ray fi ndings and the various blood parameters, a diagnosis of bronchopulmonary pneumonia with ARDS with septic shock was made. The patient was started on injection amikacin 50 mg BD IV. ABSTRACTA case report of a possible adverse drug reaction to 10% parenteral aminoacid formulation in a 5½ month male patient diagnosed with bronchopulmonary pneumonia with acute respiratory distress syndrome in septic shock, is presented. There was a temporal relationship between the administration of the parenteral amino acid formulation and the onset of the exanthem. This was further evidenced by the regression of the exanthem following the discontinuation of the formulation. The causality assessment of this adverse drug reaction has been done, and the likely causes of this hypersensitivity reaction have been analyzed.